A nanomedical approach for the rapid identification of viruses using electrochemical biosensors
Authors:
K. Dunovská 1; E. Klapková 1; M. Fořtová 1; J. Werle 1; J. Petrus 1; T. Grondžák 1; B. Hosnedlová 2; K. Kotaška 1
; J. Čepová 1; R. Průša 1; R. Kizek 1,2
Authors place of work:
2. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Motol, Praha, Ústav lékařské chemie a klinické biochemie, Přednosta: prof. MUDr. Richard Průša, CSc.
1; 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice, Praha, Klinika pediatrie a dědičných poruch metabolismu, Přednosta: prof. MUDr. Tomáš Honzík, Ph. D.
2
Published in the journal:
Prakt. Lék. 2022; 102(4): 171-176
Category:
Reviews
Summary
Aim: The review provides basic practical information about the use of biosensors in the rapid diagnosis of viral pathogens. Results: Thanks to evolutionary changes in the genome, viruses jump into the human population, where they cause serious epidemics. Rapid POCT diagnostic tools based on biosensors will enable their use for clinical diagnosis needs outside of specialized laboratories. The combination of these devices with the techniques of 3D printing, microfluidic systems, nanotechnology and electrochemical detection significantly increases the usability of biosensors. Intensive research is carried out on a wide range of viruses, e.g. HIV, Ebola, influenza, hepatitis viruses. In connection with the global covid-19 pandemic, the development of nanobiosensors is currently focused primarily on the detection of SARS-CoV-2.
Conclusion: Available literature data suggest that fast sensors and biosensors have considerable clinical potential for the use in POCT.
Keywords:
nanomedicine – Nanotechnology – biosensor – medical applications – virus detection
Zdroje
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General Practitioner
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