Congenital adrenal hyperplasia, defect of 17α-hydroxylase as a rare cause of hypertension and hypocalaemia

Česká verzia

Authors: V. Olšovská ¹; J. Šulcová ²; A. Hondlová ¹; H. Šiprová ¹
Authors place of work: II. interní klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta doc. MUDr. Miroslav Souček, CSc. ¹; Oddělení steroidních hormonů Endokrinologického ústavu, Praha, ředitel doc. MUDr. Vojtěch Hainer, CSc. ²
Published in the journal: Vnitř Lék 2005; 51(2): 226-230
Category: Case Reports

Summary

Authors describe infrequently occurring case of congenital adrenal hyperplasia, partial defect of 17α-hydroxylase in female patient with hypertension, hypocalaemia, menstrual cycle disorders and sterility. Diagnosis was established on the basis of native examination of steroid spectrum together with both stimulation and suppression tests and CT examination. After the treatment with dexamethason was established, the blood pressure and electrolyte levels reached the correction. This report supports the importance of the whole steroid spectrum examination in the patients with this symptomatology in order to eliminate rare causes of endocrine hypertension.

Key words:
congenital adrenal hyperplasia – endocrine hypertension – hypocalaemia – defect of 17α-hydroxylase

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