Can we cure atrial flutter with radiofrequency ablation in an hour?

Česká verzia

Authors: Z. Stárek ¹; L. Zaoral ¹; P. Leinveber ¹; L. Haman ²; Z. Csanádi ³; D. Heřman Za Řešitele Registru Easther ⁴
Authors place of work: I. interní kardio-angiologická klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta prof. MUDr. Jiří Vítovec, CSc., FESC ¹; I. interní klinika Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. Jan Vojáček, DrSc., FESC ²; Kardiologické centrum Lékařské fakulty Univerzity, Szeged, Maďarsko, přednosta prof. MUDr. Miklós Csanády ³; III. interní - kardiologická klinika 3. lékařské fakulty UK a FN Královské Vinohrady, Praha, přednosta prof. MUDr. Petr Widimský, DrSc., FESC ⁴
Published in the journal: Vnitř Lék 2006; 52(2): 132-136
Category: Original Contributions

* za řešitele registru EASTHER

Summary

Background:
Radiofrequency ablation of common atrial flutter requires the creation of a complete transmural ablation line across cavotricuspid region to achieve bidirectional conduction block. Irrigated tip catheters facilitate rapid achievement of this block by creation larger and deeper lesions. The EASTHER registry was organized to collect data about the efficacy of the procedure in small and middle volume centres in Central and Eastern Europe, all using THERMOCOOL^®catheter technology.

Methods:
Easther is a prospective registry (April 2002 - February 2003). 133 consecutive patients (81.1 % male, age 59.0 ± 10.4 years, range 30 - 81 years) with common atrial flutter were enrolled. Coincidence with atypical flutter was observed in 2.7 %. Patients had a history of flutter of 31.0 ± 53.6 month (range 1 - 403) and concomitant atrial fibrillation was observed in 42.9 %. Structural heart disease was present in 38.9 %. Amount of re-ablated cases was 14 %. RF energy was applied during 60 sec in power-controlled mode at a setting between 40 to 50 W with an average flow rate of 19.0 ml/min.

Results:
Acute success rate defined as bi-directional block was achieved in 93.1 %, although 94.7 % of cases were assessed successful by the treating electrophysiologist. Average number of RF applications was 12.0 ± 7.0 (range 2 - 40) per procedure. Average delivered power varied between a minimum of 36.1 ± 15.1 W till a maximum of 45.3 ± 13.0 W, while the average maximum temperature observed at the same time was varied between 39.0 ± 3.4 ºC and 45.4 ± 4.0 ºC. Total procedure time was 100.1 ± 42.7 min (range 20 - 280 min) and fluoroscopy time was 15.8 ± 9.6 min (range 4 - 45 min). In comparable French TC registry Average total and fluoroscopy time were 46.4 ± 33.6 min, and 10.0 ± 6.8 min resp. In the Middle European centres total and fluoroscopy time was 96.1 ± 40.9 min, and 15.0 ± 8.9 min resp. In centres from Eastern Europe it was 120.3 ± 51.2 min, and 20.4 ± 11.9 min resp. Two adverse events were reported. Both patients had strong chest pain during ablation. These results are comparable with the literature data published.

Conclusions:
Irrigated tip catheters are effective and safe in ablation of common atrial flutter. This technology helps to accelerate and facilitate achievement of bi-directional isthmus block. Most of procedures were terminated to one hour in experienced centers in France as early as 2002. Procedures not exceeding one hour are feasible in case of spreading this method as method of first choice with gaining of experiences in centres of Middle and Eastern Europe.

Key words:
common atrial flutter - radiofrequency ablation - irrigated tip catheter

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