Diabetic skin changes from the dermatological point of view

Česká verzia

Authors: K. Ettler
Authors place of work: Klinika nemocí kožních a pohlavních Lékařské fakulty UK a FN, Hradec Králové, přednosta doc. MUDr. Karel Ettler, CSc.
Published in the journal: Vnitř Lék 2006; 52(5): 454-458
Category: Diabetes and other subjects (infection, dermatovenerology and rheumatology) Hradec Králové 3 to 4 June 2005

Summary

Even a half of diabetic patients are suffering from skin troubles. Hyperglykemia causes skin changes leading to higher incidence of bacterial and mycotic infections, provokes skin degenerative processes, macro- and microangiopathy and neuropathy. Diabetic dermopathy, rubeosis, bullousis and scleredema are based on these changes. Other skin diseases including necrobiosis lipoidica, granuloma anulare, vitiligo, perforating folliculitis accompany diabetes frequently but their etiopathogenesis is not clear.

Key Words:
diabetes mellitus - skin complications

Zdroje

1. Vohradníková O, Perušičová J. Kožní projevy při diabetes mellitus. Praha: Maxdorf 1996; 1-159.

2. Najdawi F, Fa´ouri M. Frequency and types of skin disorders and associated diabetes mellitus in elderly Jordanians. East Mediterr Health J 2002; 8: 574-578.

3. Boulton AJ, Kirsner RS, Vileikyte L. Clinical practice. Neuropathic diabetic foot ulcers. N Engl J Med 2004; 351: 48-55.

4. Saap LJ, Donohue K, Falanga V. Clinical classification of bioengineered skin use

and its correlation with healing of diabetic and venous ulcers. Dermatol Surg 2004; 30: 1095-1100.

5. Dang CN, Boulton AJ. Changing perspectives in diabetic foot ulcer management.

Int J Low Extrem Wounds 2003; 2: 4-12.

6. Hilton JR, Williams DT, Beuker B et al. Wound dressings in diabetic foot disease. Clin Infect Dis 2004; 39(Suppl 2): 100-103.

7. Pinzur MS, Slovenkai MP, Trepman E et al. Guidelines for diabetic foot care: recommendations endorsed by the Diabetes Committee of the American Orthopaedic Foot and Ankle Society. Foot Ankle Int 2005; 26: 113-119.

8. Treece KA, Macfarlane RM, Pound N et al. Validation of a system of foot ulcer classification in diabetes mellitus. Diabet Med 2004; 21: 987-991.

9. Rajagopalan S. Serious infections in elderly patients with diabetes mellitus. Clin Infect Dis 2005; 40: 990-996.

10. Csomor J, Nikolova R, Sinko J et al. Mucormycosis. Orv Hetil 2004; 145: 2507-2513.

11. Wigington G, Ngo B, Rendell M. Skin blood flow in diabetic dermopathy. Arch Dermatol 2004; 140: 1248-1250.

12. Thomas VJ, Patil KM, Radhakrishnan S et al. The role of skin hardness, thickness, and sensory loss on standing foot power in the development of plantar ulcers in patients with diabetes mellitus--a preliminary study. Int J Low Extrem Wounds 2003; 2: 132-139.

13. Ioannidou DI, Krasagakis K, Stefanidou MP et al. Scleredema adultorum of Buschke presenting as periorbital edema: a diagnostic challenge. J Am Acad Dermatol 2005; 52(Suppl 1): 41-44.

14. Vinik AI. Advances in diabetes for the millennium: new treatments for diabetic neuropathies. Med Gen Med 2004; 6: 13.

15. Kostler E, Wollina U. Ulcerated necrobiosis lipoidica: a combined treatment approach with dermatosurgery and PUVA. Int J Low Extrem Wounds 2003; 2: 243-245.

16. Lamba S, Krishtul A, Tan MH et al. Acanthosis nigricans in a plaque of scleredema on the back of a diabetic patient: a case report. Int J Dermatol 2005; 44: 45-47.

17. Scheinfeld NS. Obesity and dermatology. Clin Dermatol 2004; 22: 303-309.

18. Raubenheimer PJ, Lewitt NS. Insulin allergy. S Afr Med J 2004; 94: 428-429.