Secondary dyslipidemias and their treatment

Česká verzia

Authors: V. Soška
Authors place of work: Oddělení klinické biochemie FN u sv. Anny Brno, přednosta doc. MUDr. Vladimír Soška, CSc.
Published in the journal: Vnitř Lék 2007; 53(4): 396-400
Category: Reviews

Summary

Secondary dyslipidemias may develope due to other diseases or due to several important enviromental influences. The most common are secondary dyslipidemias due to following diseases: undercontrolled diabetes mellitus, hypothyreosis, hyperfunction of suprarenal glands, cholestasis, chronic renal diseases (chronic renal failure, nephrotic syndrom), acute infectious diseases. Very common cause of secondary dyslipidemia is abusus of alcohol. Also some drugs may induce dyslipidemias: corticosteroides, immunosupresive drugs, less frequently also thiazid diuretics and non-selective beta-blockers. During pregnancy is dyslipidemia physiologic. If causal treatment of secondary dyslipidemia is possible, hypolipidemic drugs are not indicated. Start of treatment with hypolipidemic drugs depends on the extent of risk of fatal cardiovascular event, not on the blood lipids level. When hypolipidemic treatment is indicated, the choice of the drug and it´s dose depends also on the type od primary disease and it´s severity.

Key words:
secondary dyslipidemia - diabetes mellitus - hypothyreosis - steatosis hepatis - chronic renal failure - immunosupressive drugs - alcohol

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