Inflammatory reaction and its importance in the course of tumour process

Česká verzia

Authors: D. Hlávková ¹; O. Kopecký ^2,3; Š. Lukešová ^2,3
Authors place of work: Ústav klinické imunologi e a alergologi e Lékařské fakulty UK a FN Hradec Králové, přednosta prof. RNDr. Jan Krejsek, CSc. ¹; Oddělení klinické imunologi e a alergologi e Oblastní nemocnice Náchod, a. s., přednosta doc. MUDr. Otakar Kopecký, CSc. ²; II. interní klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Jaroslav Malý, CSc. ³
Published in the journal: Vnitř Lék 2008; 54(9): 821-826
Category: Review

Summary

This article gives basic informati on abo ut the formati on and the co urse of the inflammatory re acti on, which is the important adaptati on mechanism of the organism on the vari o us external and internal injurants. The main attenti on is fixated on the role of the immune system in the co urse of the inflammatory re acti on. It de als with the presence and the sense of the inflammatory re acti on in the tumo ur environment in more detail. It gives the short informati on abo ut the mechanisms of the antitumo ur defence. The influence of the inflammatory re acti on on the genesis, the co urse and the progressi on of the tumo ur dise ase is discussed in the third chapter.

Key words:
inflammatory re acti on – immune system – antitumo ur imunity – tumo ur microenvironment – cytokines – chemokines

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