Metabolic syndrome and cardiovascular disease

Česká verzia

Authors: J. Špinar ¹; J. Vítovec ²
Authors place of work: Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jindřich Špinar, CSc., FESC ¹; I. interní kardio-angiologická klinika Lékařské fakulty MU a FN u sv. Anny Brno, přednosta prof. MUDr. Jiří Vítovec, CSc., FESC ²
Published in the journal: Vnitř Lék 2009; 55(7-8): 653-658
Category: 134th Internal Medicine Day - 23rd Vanysek's Day Brno 2009 - Vanysek's Lecture

Summary

We provide an overview of the current views on the association between metabolic syndrome and cardiovascular disease. Insulin resistance, frequently onsetting from obesity and associated hypercholesterolemia, hypertension and diabetes mellitus, is the common denominator. We also highlight another risk factor – heart rate, closely related to the prognosis of healthy individuals, patients with hypertension and patients following myocardial infarction. Finally, we present the results of the CRUSADE study that has clearly described the association between obesity and age and the first manifestation of the ischemic heart disease.

Key words:
metabolic syndrome – diabetes mellitus – hypertension – heart rate – obesity

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