Serum lipoprotein profile in newly recognized arterial hypertension. The role of atherogenic lipoproteins in the pathogenesis of disease

Česká verzia

Authors: S. Oravec; A. Dukát; P. Gavornik; M. Čaprdna; M. Kučera
Authors place of work: II. interná klinika Lekárskej fakulty UK a FNsP Bratislava, Slovenská republika, prednosta prof. MU Dr. Andrej Dukát, CSc., FESC
Published in the journal: Vnitř Lék 2010; 56(9): 967-971
Category: 60th Birthday - Andrej Dukat MD, Csc., FESC

Summary

New examination approaches in biochemical analysis of lipoproteins can identify and quantify atherogenic plasma lipoproteins, including small dense LDL and characterise a lipoprotein spectrum as a non‑atherogenic lipoprotein profile phenotype A, respectively as an atherogenic lipoprotein profile phenotype B. Identification of a non‑aterogenic hypercholesterolemia (48%), atherogenic hypertriglyceridemia (93%), atherogenic normolipemia (13%) in patients with arterial hypertension and an atherogenic normolipemia in control group of healthy subjects (7%), is an essential contribution of this new laboratory diagnostics.

Key words:
atherogenic lipoprotein profile – non‑atherogenic hypercholesterolemia – atherogenic normolipemia

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