Cardiovascular medications in elderly
Authors:
H. Matějovská Kubešová; P. Weber; H. Meluzínová; J. Matějovský
Authors place of work:
Klinika interní, geriatrie a praktického lékařství Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednostka prof. MUDr. Hana Matějovská Kubešová, CSc.
Category:
Online
Summary
Authors analyze recommended groups of medications and their risks for elderly patients. Angiotensinconverting enzyme blockers and their influence on the endothelial dysfunction, but the risk of hyperpotassemia are showed. The risk of gastrointestinal bleeding during the treatment with antiagregants and anticoagulants, the risk of bradycardia in beta-blockade, possible interactions with other medications lowering the heart rate are discussed. Attention is paid to calcium channel blockers, diuretics and digoxin. Important conclusions for practice are resumed at the end of the article.
Key words:
angiotensinconverting enzyme inhibitors - antiagregants - beta-blockers - statins - calcium blockers - diuretics - digoxin - pharmacotherapy in elderly - unwanted side effects - interaction of medications
Zdroje
1. Beers MH, Ouslander JG, Rollingher I et al. Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med 1991; 151: 1825-1832.
2. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med 1997; 157: 1531-1536.
3. Matějovský J. Komplexní pohled na funkční a zdravotní stav seniorů žijících ve svém vlastním prostředí. Diplomová práce. Brno: LF MU 2007.
4. Konopa J, Bullo B, Rutkowski B. Life threatening drug-induced hyperkaliemia - case report. Pol Arch Med Wewm 2006; 115: 238-242.
5. Topinková E. Geriatrie pro praxi. Praha: Galén 2005.
6. Fialová D, Topinková E, Gambassi G et al. AdHOC Project Research Group. Potentially Inappropriate Medication Use Among Elderly Home Care Patients in Europe. JAMA 2005; 293: 1348-1358.
7. European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery. Camm AJ, Kirchhof P, Lip GY et al. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J 2010; 31: 2369-2429.
8. Cleland JGF, Coletta AP, Torabi A et al. Clinical trials update from the European Society of Cardiology heart failure meeting 2009: CHANCE, B-Convinced, CHAT, CIBIS-ELD and Signal HF. Eur J Heart Fail 2009; 11: 802-805.
9. Kubešová H, Weber P, Polcarová V et al. Akutní koronární syndrom u seniorů nad 75 let. Čes Ger Rev 2008; 6: 141-146.
10. Manderbacka K, Keskimäki I, Reunanen A et al. Equity in the use of antithrombotic drugs, beta-blockers and statins among Finnish coronary patients. Int J Equity Health 2008; 7: 16-20.
11. Pretnar-Oblak J, Sebestjen M, Sabovic M. Statin treatment improves cerebral more than systemic endothelial dysfunction in patients with arterial hypertension. Am J Hypertens 2008; 21: 674-678.
12. Pregelj P. Involvement of cholesterol in the pathogenesis of Alzheimer’s disease: Role of statins. Psychiatr Danub 2008; 20: 162-167.
13. Duron E, Hanon O. Vascular risk factors, cognitive decline and dementia. Vasc Health Risk Manag 2008; 4: 363-381.
14. Kalvach Z, Zadák Z, Jirák R et al. Geriatrie a gerontologie. Praha: Grada publishing 2004.
Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Internal Medicine
Najčítanejšie tento týždeňNajčítanejšie v tomto čísle
- Antibiotic treatment of acute bacterial infections
- Management of obesity – options, effectiveness and perspectives
- Genetics of monogenic forms of diabetes
- Modern technologies in diabetology. CSII (Continuous Subcutaneous Insulin Infusion) and CGM (Continuous Glucose Monitoring) in clinical practice