Liver transplants in viral hepatitides

Česká verzia

Authors: L. Husová
Authors place of work: Centrum kardiovaskulární a transplantační chirurgie Brno, ředitel doc. MU Dr. Petr Němec, CSc.
Published in the journal: Vnitř Lék 2013; 59(8): 694-697
Category:

Summary

The authors present their own results of liver transplants over the last 30 years (from 2 February 1983 to 31 December 2012). For the respective period, 451 patients underwent a transplant in the Brno Transplantation Centre. Ten out of 451 patients (2.2%) underwent transplants for the indication of cirrhosis caused by viral hepatitis B in the Brno Transplantation Centre. The first liver transplant indicated due to viral hepatitis B was performed in 1994. Out of the ten patients, 3 died (30%). Forty‑ one out of 451 patients (9%) underwent liver transplant for cirrhosis caused by viral hepatitis C. The first liver transplant indicated due to viral hepatitis B was performed in 1991. A total of 21 patients out of 41 (51%) were treated with antiviral therapy; 27 out of 41 (66%) developed a recurrence after the liver transplant. Out of the 41 patients who underwent a liver transplant for viral hepatitis C indication, a total of 15 (36.6%) died.

Key words:
orthotopic liver transplantation – indication – cirrhosis – hepatitis B virus – hepatitis C virus

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