New aspects of hormone replacement therapy

Česká verzia

Authors: Tomáš Fait
Authors place of work: Gynekologicko-porodnická klinika 1. LF UK a VFN Praha, přednosta prof. MUDr. Alois Martan, DrSc.
Published in the journal: Vnitř Lék 2014; 60(11): 942-947
Category: Reviews

Summary

All existing recommendations sign hormone replacement therapy (HRT) as first therapy for acute climacteric syndrome. The low dose vaginal therapy is the first choice for prevention and therapy of urogenital atrophy and its complications. Early start of HRT has neutral or slightly beneficial influence on ischaemic heart disease. It is sure that HRT is effective in prevention and therapy of postmenopausal osteoporosis. Long term therapy must be individualized on base of benefits to risks ratio with differences by type of HRT.

Key words:
acute climacteric syndrome – hormone replacement therapy – ischaemic heart disease – osteoporosis – urogenital atrophy

Zdroje

1. Fait T, Donát J, Jeniček J et al. Doporučení pro hormonální substituční terapii v postmenopauze. Čes Gynek 2010; 75(2): 109–110.

2. Birkhauser MH, Panay N, Archer DF et al. Updated recommendations for hormone replacement therapy in the peri- and postmenopause. Climacteric 2008; 11(2): 108–123.

3. Utian WH, Archer DF, Bachmann GA. Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society. Menopause 2008; 15(4 Pt 1): 584–602.

4. Archer DF, Baber RJ, Barlow D et al. Updated IMS recommendations on postmenopusal hormone therapy and preventive strategie for midlife health. Climacteric 2011; 14(3): 302–320.

5. Sannten RJ, Allred DC, Ardoin SP et al. Postmenopausal Hormone Therapy. An Edocrine Society Scientific Statement. J Clin Endocrinol Metabol 2010; 95(7 Suppl 1): S1-S66.

6. Nelson HD, Walker M, Zakher B et al. Menopausal hormone therapy for the primary prevention of chronic medication: a systematic review to update the U.S. Preventive Services Task Force recommendations. Ann Intern Med 2012; 157(2): 104–113.

7. Marjoribanks J, Farquhar C, Roberts H et al. Long term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev 2012; 7: CD004143. Dostupné z DOI: <http://dx.doi.org/10.1002/14651858.CD004143.pub4>.

8. Colditz GA, Willett WC, Stampfer MJ et al. Menopause and the risk of coronary heart disease in women. N Engl J Med 1987; 316(18): 1105–1110.

9. Busch TL, Barrett-Connor E, Cowan LD et al. Cardiovascular mortality and noncontraceptive use of estrogen in women. Circulation 1987; 75(6): 1102–1109.

10. Sullivan JM, Vander Zwaag R, Hughes JP et al. Estrogen replacement and coronary artery disease. Arch Intern Med 1990; 150(12): 2557–2562.

11. Sullivan JM, Vander Zwaag R, Lemp GF et al. Postmenopausal estrogen use and coronary atherosclerosis. Ann Intern Med 1988; 108(3): 358–363.

12. Gruchow HW, Anderson AJ, Barboriah JJ et al. Postmenopausal use of estrogen and occlusion of coronary arteries. Am Heart J 1988; 115(5): 954–963.

13. Grodstein F, Manson JE, Colditz GA et al. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med 2000; 133(12): 933–941.

14. Hulley S, Grady D, Bush T et al. Randomised trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998; 280(7): 605–613.

15. Clarke S, Kelleher J, Lloyd-Jones H et al. A study of hormone replacement therapy in postmenopausal women with ischaemic heart disease: the Papworth HRT atherosclerosis study. BJOG 2002; 109(9): 1056–1062.

16. Angerer P, Stork S, Kothny W et al. Effect of postmenopausal hormone replacement on atherosclerosis in femoral arteries. Maturitas 2002; 41(1): 51–60.

17. Waters P, Alderman EL, Hsia J et al. Effects of HRT and antioxidant vitamin supplememts on coronary atherosclerosis in postmenopausal women. JAMA 2002; 288(19): 3433–3440.

18. Hodis HN, Mack WJ. Atheroslerosis Imaging methods: Assessing cardiovascular disease and evaluating the role of estrogen in prevention of atherosclerosis. Am J Cardiol 2002; 89(12A): 19E-27E; discussion 27E.

19. Rossouw JE, Anderson GL, Prentice RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women‘s Health Initiative randomized controlled trial. JAMA 2002; 288(3): 321–333.

20. Anderson GL, Limacher M, Assaf AR et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women‘s Health Initiative randomized controlled trial. JAMA 2004; 291(14): 1701–1712.

21. Salpeter SR, Walsh JME, Greyber E et al. Mortality associated with HRT in younger and older women. J Gen Intern Med 2004; 19(7): 791–804.

22. Rossouw JE, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007; 297(13): 1465–1477.

23. Allison MA, Manson JE, Langer RD et al. Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women‘s Health Initiative coronary artery calcium study. Menopause 2008; 15(4 Pt 1): 639–647.

24. Collins P, Rosano G, Casey C et al. Management of cardiovascular risk in peri-menopausal woman. Eur Heart J 2007; 28(16): 2028–2040.

25. Manson JE. The Kronos Early Estrogen Prevention Study by Charlotte Barker. Womens Health (Lond Engl) 2013; 9(1): 9–11.

26. Schierbeck LL, Rejnmark L, Tofteng CL et al. Efect of HRT on cardiovascular events in recently postmenopausal women. BMJ 2012; 345: e6409. Dostupné z DOI: <http://dx.doi.org/10.1136/bmj.e6409>.