Distribution of values of glycated haemoglobin in a population with type 2 diabetes: a project Valetudo

Česká verzia

Authors: Milan Kvapil
Authors place of work: Interní klinika 2. LF UK a FN Motol Praha, přednosta prof. MUDr. Milan Kvapil, CSc., MBA
Published in the journal: Vnitř Lék 2015; 61(1): 81-83
Category: Letters to Editor

Summary

Currently, there are no available data on distribution of the values of glycated haemoglobin in patients with type 2 diabetes in the Czech Republic. More frequent, efficacy and early application of new antidiabetic agents is limited by indication criterion which restricts the payment of this therapy for patients with poorly compensated diabetes defined by threshold value of 60 mmol/mol (6% IFCC). The study Valetudo analyzed distribution of glycated haemoglobin values in the random population of patients with type 2 diabetes and showed that within the critical range from 43 mmol/mol to 80 mmol/mol is the average frequency of patients from the whole population of 1.88%/1 mmol/mol glycated haemoglobin. Interpretation of data from cross-sectional studies is very difficult as they involve patients before treatment (possibly before the intensification of therapy) and also patients successfully treated.

Key words:
diabetes mellitus type 2 – distribution of HbA_1c – glycated haemoglobin – HbA_1c – Valetudo project

Zdroje

1. Charvát J, Kvapil M. Vztah terapie hyperglykémie a riziko ischemické choroby srdeční: rok 2010. In: Kvapil M (ed): Diabetologie 2010. Triton: Praha: 2010: 35–57. ISBN 978–80–7387–381–3.

2. Gerstein HC, Miller ME, Genuth S et al. ACCORD Study Group. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med 2011; 364(9): 818–828.

3. Všeobecná zdravotní pojišťovna České republiky. Preskripční omezení. Dostupné z WWW: <http://www.vzp.cz/poskytovatele/ciselniky/preskripcni-omezeni>.

4. Doležal T, Kvapil M. Kvalita léčby diabetu 2. typu v ČR. In: Kvapil M (ed). Diabetologie 2010. Triton: Praha 2010: 266–282. ISBN 978–80–7387–381–3.

5. Kvapil M. Projekt Valetudo. Kazuistiky v diabetologii 2010; 8(3): 23–26.

6. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352(9131): 837–853.