Myocardial injury after carbon monoxide intoxication in suicide attempt, with features of both toxic and tako-tsubo cardiomyopathy: case report

Česká verzia

Authors: Radek Vančata ¹; Jan Lhotský ¹; Václav Beránek ¹; Josef Krištof ²; Richard Rokyta ¹
Authors place of work: Komplexní kardiovaskulární centrum – kardiologické oddělení, FN Plzeň, pracoviště Lochotín ¹; Klinika anesteziologie, resuscitace a intenzivní medicíny LF UK a FN Plzeň ²
Published in the journal: Vnitř Lék 2018; 64(7-8): 797-801
Category: Case Reports

Kazuistika byla prezentována ve zkrácené podobě jako poster na XXV. výročním sjezdu České kardiologické společnosti v Brně 7. 5.–10. 5. 2017.

Summary

Severe carbon monoxide intoxication may cause tissue injury by hypoxemia and histotoxicity. The affection of the heart muscle often leads to transient global or regional systolic dysfunction of left ventricle or both ventricles and increased occurences of malignant arrhytmias. On the contrary, stress-induced cardiomyopathy is described as temporary segmental loss of contractility, mostly in apical segments of the left ventricle with mid- and basal sparing and less common hypokinesias in mid- or basal parts, or affection of both ventricles. This case report is dedicated to a 34-years old male, who was admitted to the department of emergency medicine after suicide attempt by carbon monoxide poisoning. Echocardiography at admission showed akinesias of midsegments of left ventricle and severe hypokinesias of apical and basal segments. Despite severe cardiogenic shock, adequate therapeutic management including mechanical ventilation, normobaric oxygenotherapy and catecholamine treatment led to a complete somatic recovery after 2 weeks, and without any permanent hypoxemic brain injury. Our case might be a coincidence of toxic cardiomyopathy, caused by carbon monoxide poisoning, and takotsubo cardiomyopathy as a result of long term exposition to combined stress factors that may lead even to a suicide attempt. Both types of cardiomyopathies often occure simultaneously due to similar pathophysiologic mechanisms. Both tako-tsubo and toxic cardiomypathy have good prognosis after overcoming the acute phase.

Key words:

carbon monoxide – cardiogennic shock – cardiomyopathy – suicide – tako-tsubo cardiomypathy

Zdroje

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