Lung diseases and autoimmune hemolytic anemia associted with IgG4 disease

Česká verzia

Authors: Martina Doubková ¹; Radoslav Matěj ²; Zita Chovancová ³; Michael Doubek ^4,5
Authors place of work: Klinika nemocí plicních a tuberkulózy LF MU a FN Brno, pracoviště Bohunice ¹; Ústav patologie a molekulární medicíny 3. LF UK a Thomayerovy nemocnice, Praha ²; Ústav klinické imunologie a alergologie LF MU a FN u sv. Anny Brno ³; Interní hematologická a onkologická klinika LF MU a FN Brno pracoviště Bohunice ⁴; Středoevropský technologický institut MU Brno ⁵
Published in the journal: Vnitř Lék 2020; 66(4): 47-52
Category:

Summary

IgG4 related disease (IgG4-RD) is a rare and relatively new group of systemic inflammatory diseases characterized by inflammatory, fibrotic or sclerotic involvement of one or more organs accompanied by increased IgG4plasma cells tissue infiltration andusually elevated serum IgG4(IgG4 > 1.35g/l, normal range 0.08–1.40 g/l) level. Histopathological findings are crucial for the diagnostics of this disease. The authors present a case report of a patient with IgG4 associated disease manifested by a rare combination of autoimmune hemolytic anemia and pulmonary involvement.

Keywords:

autoimmune haemolytic anemia – IgG4 associated disease – interstitial lung disease

Zdroje

1. Laccarino L, Talarico R, Scirè CA, et al. IgG4-related diseases: state of the art on clinical practice guidelines. RMD Open 2019; 4: (Suppl. 1): e000787.

2. Umehara H, Okazaki K, Nakamura T, et al. Current approach to the diagnosis of IgG4-related disease -Combination of comprehensive diagnostic and organspecific criteria. Mod Rheumatol 2017; 27: 381–391.

3. Bozzala Cassione E, Stone JH. IgG4-related disease. Curr Opin Rheumatol 2017; 29: 223–227.

4. Stone JH, Zen Y, Deshpande V IgG4-related disease. N Engl J Med. 2012; 366: 539–551.

5. Stone JH, Khosroshahi A, Deshpande V, et al. Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis Rheum 2012; 64: 3061–3067.

6. Umehara H, Okazaki K, Masaki Y, et al. Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011. Mod Rheumatol 2012; 22: 21–30.

7. Matusi S, Yamamoto H, Minamoto S, et al. Proposed diagnostic criteria for IgG4-related respiratory disease. Respir Investig 2016; 54: 130–132.

8. Kamisawa T, Funata N, Hayashi Y, et al. A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol 2003; 38: 982–984.

9. Masaki Y, Dong L, Kurose N, et al. Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome. Analysis of 64 cases of IgG4-realted disorders. Ann Rheum Dis 2009; 68: 1310–1315.

10. Mikulová Š, Jílek D, Richter J. Nemoc asociovaná s IgG4. Úvod, patogeneze, diagnostika. 1. část. Alergie 2015; 17: 16–24.

11. Mikulová Š, Jílek D, Richter J. Nemoc asociovaná s IgG4. Klinický obraz, orgánová postižení a terapie. 2. Část. Alergie 2015; 17: 91–99.

12. Zen Y, Fujii T, Harada K, et al. Th2 and regulatory immune reactions are incresased in immunoglobulin G4-related sclerosing pancreatiits and cholangiitis. Hepatology 2007; 45: 1538–1546.

13. Aalberse RC, Stapel SO, Schuurman J et al. Immunoglobulin G4: an odd antibody. Clin Exp Allergy 2009; 39: 469–477.

14. Satoguina JS, Weyand E, Larbi J, et al. T regulatory-1 cells induce IgG4 production by B cells: role of IL-10. J Immunol 2005; 174: 4718–4726.

15. Desphande V, Khorohahi A. Diagnostic guidelines for IgG4-related disease with a focus on histophatological criteria. Diagnostic histopathology 2013; 19: 119–127.

16. Nirula A, Glaser SM, Kalled SL, et al. What is IgG4? A review of the biology of a unique immunoglobulin subtype. Curr Opin Rheumatol 2011; 23: 119–124.

17. Anhalt GJ, Labib RS, Voorhees JJ et al. Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease. N Engl J Med 1982; 306: 1189–1196.

18. Beck jr. LH, Salant DJ. Membranous nephropathy: recent travels and new roads ahead. Kidney Int 2010; 77: 765–770.

19. Plomp JJ, Hujbers MG, van der Maarel SM, et al. Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis. Ann NY Acad Sci 2012; 1275: 114–122.

20. Shiokawa M, Kodama Y, Kuriayma K, et al. Pathogenicity of IgG in patients with IgG in patients with IgG4-related disease. Gut 2016; 65: 1322–1332.

21. Khosroshahi A, Wallace ZS, Crowe JL, et al. International consensus guidance statement on the management and treatment of IgG4-related disease. Arthiritis Rheumatol 2015; 67: 1688–1699.

22. Ghazale A, Chari ST, Zhang L, et al. Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy. Gastroenterology 2008; 134: 706–715.

23. Raina A, Yadav D, Krasinskas AM, et al. Evaluation and management of autoimmune pancreatitis: experience at al large US center. Am J Gastroenterol 2009; 104: 2295–306.

24. Losse S, Žurková M. Plicní projevy nemoci asociované s IgG4. Postgrad Med 2017; 19: (Suppl. 2): 50–54.

25. Khoroshahi A, Bloch DB, Desphande V, et al. Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4related systemic disease. Arthritis Rheum 2010; 62: 1755–1762.

26. Adam Z, Chovancová Z, Nová M, et al. Remise „the disease associated/related with immunoglobulin IgG4“ provázeného mnohočetnou lymfadenopatií po léčbě rituximabem a dexametazonem: kazuistika. Vnitř Lék 2018; 64: 290–299.

27. Hasegawa S, Mine S, Hagiwara S. IgG4-related disease combined with autoimmune hemolytic anemia and steroid -responsive transient hypercalcemia. Clin Med Insights Case Rep 2015; 8: 51–55.

28. Wang KC, Liao HT, Tsai CY IgG4-related disease coexisting with autoimmune haemolytic anaemia. BMJ Case Rep 2018; pii: bcr-2018–224814.

29. Yoshida M, Marumo Y, Naitoh I, et al. Autoimmune hemolytic anemia obscured by the obstructive jaundice associated with IgG4-related sclerosing cholangitis in a patient with type 1 autoimmune pancreatitis: a case report and review of the literature. Intern Med 2018; 57: 1725–1732.

30. Noguchi S, Yatera K, Jinbo M, et al. IgG4-related lung disease associated with autoimmune hemolytic anemia: a case report and a literature review. Intern Med 2016; 55: 2469–2474.

31. Masutani H, Okuwaki K, Kida M, et al. First case of IgG4-related sclerosing cholangitis associated with autoimmune hemolytic anemia. World J Gastroenterol 2014; Doi: 10.3748/wjg.v20.i26.8740.