The mortality risk of patients hospitalized for ischemic stroke between 2003 and 2019
Authors:
Lenka Kielbergerová 1; Otto Mayer Jr. 1,2; Jan Bruthans 1,3
Authors place of work:
Neurochirurgická klinika, Fakultní nemocnice, Plzeň
1; II. interní klinika, Univerzita Karlova, Lékařská fakulta a Fakultní nemocnice, Plzeň
2; Biomedicínské centrum, Univerzita Karlova, Lékařská fakulta a Fakultní nemocnice, Plzeň
3; Centrum kardiovaskulární prevence, Thomayerova nemocnice a 1. lékařská fakulta Univerzity Karlovy, Praha
4
Published in the journal:
Vnitř Lék 2022; 68(E-3): 4-11
Category:
Original Contributions
Summary
Background: Stroke represents an essential part of the burden of cardiovascular diseases. Despite specific mortality from cerebrovascular diseases decreasing in the Czech Republic since the ‘80s, the trends in case fatality and individual risk of patients who suffered from stroke remain questionable. In patients hospitalized for ischemic stroke, we evaluated the mortality trends in the last two decades.
Methods: 9076 patients (mean age 71.8, 51.9% males) hospitalized for ischemic stroke between 2003 and 2019 were followed. The vital status we ascertained up to 31.12.2020, other circumstances from the hospital information system
Results: In total, 5583 patients died during follow-up. The in-hospital fatality was 9.1%, 30-day mortality 14.2%, and 1-year mortality 28.4%. In patients hospitalized from 2003 to 2015, the 5-year mortality was 49.8%. No significant changes were noted for in-hospital fatality, 30-days, 1-year mortality, as well as 5-years mortality risk across more extensive periods (2003-07, 2008-11, 2012-15 and 2016-19). As expected, any decade of patient´s age was associated with about two-fold higher mortality risk. Intravenous thrombolysis, as part of initial management, markedly increased over time (from 2.4% in 2003-07 to 48.1% in 2016-19). However, this procedure affected beneficially only 1-year mortality risk, while regarding 5-years mortality was its effect neutral.
Conclusions: Despite favorable trends in cerebrovascular events from a population perspective, the individual prognosis of patients who have suffered a stroke remains very poor.
Keywords:
Prognosis – mortality – cerebrovascular accidents – in‑hospital fatality
Zdroje
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Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Internal Medicine
2022 Číslo E-3
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