Severe autoimune thyreotoxicosis complicated by febrile neutropenia as a result of thyreostatic therapy
Authors:
Marie Jarolímová; Michal Kazmíř
Authors place of work:
Interní oddělení, Oblastní nemocnice Kolín, a. s.
Published in the journal:
Vnitř Lék 2023; 69(E-2): 19-22
Category:
Case reports
doi:
https://doi.org/10.36290/vnl.2023.024
Summary
Hyperthyreoidism is a clinical manifestation of excessive production of thyroid hormones. In most cases pacient ´s condition allows ambulant treatment. Rarely, it can develop into an acute, life- threatening thyrotoxic crisis which has to be treated in the intensive care unit. Main therapy includes antithyroid medication, corticosteroids, beta- blockers and rehydratation, mostly parenteral. If initial treatment fails, plasmapheresis provides effective strategy.
Antithyroid medication may come with side effects as rash, digestive issues, joint pain.Agranulocystosis or acute liver lesion which leads to liver failure belong among the most severe ones. In this case we report a pacient with thyrotoxic crisis, atrial fibrilation which led to ventricular fibrilation, cor thyreotoxicum. The treatment was complicated by febrile neutropenia.
Keywords:
agranulocytosis – hyperthyreoidism – Lugol solution – total thyreoidectomy – thyrotoxic crisis
Zdroje
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Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Internal Medicine
2023 Číslo E-2
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