Non-opioid analgesics

Česká verzia

Authors: Jitka Fricová
Authors place of work: Centrum pro léčbu bolesti, KARIM 1. LF UK a VFN v Praze
Published in the journal: Čas. Lék. čes. 2018; 157: 74-78
Category: Review Article

Summary

Non-opioid analgesics are commonly used to treat mild and moderate acute and chronic pain. They can be used as monotherapy; however, they have greater efficacy in combination with weak and strong opioids. Unlike opioids, long-term use of non-steroidal anti-inflammatory drugs does not lead to physical dependence. One of the main disadvantages of the NSA is the risk of gastrointestinal side effects, especially bleeding into the digestive tract. This is increased especially in ulcerative disease and in higher doses, but also in the elderly (over 65 years), also with concomitant administration of corticosteroids, anticoagulants or other NSAIDs.

Keywords:
non-steroidal anti-inflammatory drugs, pain, paracetamol ibuprofen, metamizol, hepatic insufficiency, renal insufficiency

Zdroje

1. Kršiak M. Novinky ve farmakologii opioidů. In: Kozák J: Opioidy v léčbě bolesti. Mladá fronta, Praha, 2009: 61–76.

2. Rokyta R, Kršiak M, Kozák J (eds.). Bolest. Tigis, Praha, 2012.

3. Fricová J. Léčba orofaciální bolesti neopioidními analgetiky. Bolest 2011; 14(2): 65–68.

4. Becker DE. Pain management. Part 1: Managing acute and postoperative dental pain. Anesth Prog 2010; 57(2): 67–78.

5. Kolektiv autorů. Metodické pokyny pro farmakoterapii bolesti. Bolest 2016; 19(Suppl. 1): 1–28

Štítky

Addictology Allergology and clinical immunology Anaesthesiology, Resuscitation and Inten Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric dermatology & STDs Paediatric gastroenterology Paediatric gynaecology Paediatric surgery Paediatric cardiology Paediatric nephrology Paediatric neurology Paediatric clinical oncology Paediatric ENT Paediatric pneumology Paediatric psychiatry Paediatric radiology Paediatric rheumatology Paediatric urologist Diabetology Endocrinology Pharmacy Clinical pharmacology Physiotherapist, university degree Gastroenterology and hepatology Medical genetics Geriatrics Gynaecology and obstetrics Haematology Hygiene and epidemiology Hyperbaric medicine Vascular surgery Chest surgery Plastic surgery Surgery Medical virology Intensive Care Medicine Cardiac surgery Cardiology Clinical speech therapy Clinical microbiology Nephrology Neonatology Neurosurgery Neurology Nuclear medicine Nutritive therapist Obesitology Ophthalmology Clinical oncology Orthodontics Orthopaedics ENT (Otorhinolaryngology) Anatomical pathology Paediatrics Pneumology and ftiseology Burns medicine Medical assessment General practitioner for children and adolescents Orthopaedic prosthetics Clinical psychology Radiodiagnostics Radiotherapy Rehabilitation Reproduction medicine Rheumatology Nurse Sexuology Forensic medical examiner Dental medicine Sports medicine Toxicology Traumatology Trauma surgery Urology Laboratory Home nurse Phoniatrics Pain management Health Care Dental Hygienist Medical student

Článek Control (editing) of the genome within reach, or already in our hands?

Článek Esophagogastric junction and its tumours – comments to definition and classification

Článek Hereditary breast cancer: genetic etiology and current possibilities of prevention and surgical treatment

Článek Pathophysiology of pain and its clinical application

Článek Current and future pharmacotherapy of severe psychiatric disorders

Článek Opioids and new trends in pain therapy

Článek Back pain treatment

Článok vyšiel v časopise

Journal of Czech Physicians

2018 Číslo 2

Stáhnout celé číslo v PDF

Najčítanejšie tento týždeň

Najčítanejšie v tomto čísle