Spine metastasis of malignant melanoma detected by SPECT/CT on gallium scintigraphy
Authors:
Otto Lang 1; Martin Krbec 2
Authors place of work:
Klinika nukleární medicíny, Universita Karlova, 3. LF a FN Královské Vinohrady, Praha
1; Ortopedicko-traumatologická klinika, Universita Karlova, 3. LF a FN Královské Vinohrady, Praha
2
Published in the journal:
NuklMed 2013;2:71-75
Category:
Casuistry
Summary
A case report of 67-y-old men with cancer duplicity is presented. He suffered from prostate cancer from 2009 and from malignant melanoma on his back with a positive sentinel node from May 2010. He was treated with chemo-radiotherapy for both diseases; he was clinically stable without signs of generalization. He was evaluated with gallium scan due to malignant melanoma in August 2010 and in June 2011 in our department. Both examinations were interpreted as negative. Back pain started in February 2013, CT scan detected compression of Th9 due to metastatic infiltration. Tissue specimen withdrawn during spine stabilization in April 2013 confirmed metastasis of amelanotic malignant melanoma. Revision of gallium scans proved increased accumulation of 67Ga citrate in Th9 on the examination in June 2011 comparing to that in August 2010. The detection was made possible thanks to fusion of scintigraphic SPECT images with low-dose CT.
Key words:
malignant melanoma, spine metastasis, gallium scan, SPECT/CT
Zdroje
1. Schröer-Günther MA, Wolff RF, Westwood ME et al. F-18-fluoro-2-deoxyglucose positron emission tomography (PET) and PET/computed tomography imaging in primary staging of patients with malignant melanoma: a systematic review. Syst Rev 2012;1:62
2. Trotter SC, Sroa N, Winkelmann RR et al. A Global Review of Melanoma Follow-up Guidelines. J Clin Aesthet Dermatol 2013;6:18–26
3. Doležal J, Vižďa J, Klzo L. Zobrazení izolované metastázy maligního melanomu v pravé srdeční komoře pomocí scintigrafie s 67Galium- citrátem. Vnitr Lek 2008;54:862-865
4. Dickson PV, Gershenwald JE. Staging and prognosis of cutaneous melanoma. Surg Oncol Clin N Am 2011;20:1-17
5. Mervic L. Prognostic factors in patients with localized primary cutaneous melanoma. Acta Dermatovenerol Alp Panonica Adriat 2012;21:27-31
6. Love C, Palestro C. Altered biodistribution and incidental findings on Gallium and labeled leukocyte/bone marrow scans. Semin Nucl Med 2010;40:271-282
7. Guo H, Yang J, Shenoy N et al. Gallium-67-Labeled Lactam Bridge-Cyclized Alpha-Melanocyte Stimulating Hormone Peptide for Primary and Metastatic Melanoma Imaging. Bioconjug Chem 2009;20:2356–2363
8. Nelson B, Hayes RL, Edwards L et al. Distribution of Gallium in human tissues after intravenous administration. J Nucl Med 1972;13:92-100
9. Vižďa J, Urbanová E. Atlas galiové scintigrafie. Praha: Agentura Pankrác 2001
10. Chen WC, Tsai KD, Chen CH et al. Role of gallium-67 scintigraphy in the evaluation of occult sepsis in the medical ICU. Intern Emerg Med 2012;7:53-58
11. Basu S, Zhuang H, Torigian DA et al. Functional imaging of inflammatory diseases using nuclear medicine techniques. Semin Nucl Med 2009;39:124-145
12. Zadražil L, Libus P. Specifikace nejistých lézí na planární celotělové kostní scintigrafii s použitím SPECT/CT u onkologických pacientů. NuklMed 2013;2:25-30
13. Visioni A, Kim J. Positron emission tomography for benign and malignant disease. Surg Clin North Am 2011;91:249-266
14. Tyler DS, Onaitis M, Kherani A et al. Positron emission tomography scanning in malignant melanoma. Cancer 2000;89:1019–1025
Štítky
Nuclear medicine Radiodiagnostics RadiotherapyČlánok vyšiel v časopise
Nuclear Medicine
2013 Číslo 4
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