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preLekára.sk / Journals / Nuclear Medicine / 2018 - 3

18F-FDG PET/CT pattern of Erdheim-Chester disease – a group of Czech patients

Česká verzia

Authors: Zdeněk Řehák 1,2;  Renata Koukalová 1;  Jiří Vašina 1;  Václav Ptáčník 3;  Petr Szturz 4;  Josef Karban 5;  Jindřich Polívka 5;  Zdeněk Adam 4
Authors place of work: Oddělení nukleární medicíny, MOÚ Brno, ČR 1;  Regionální centrum aplikované molekulární onkologie, MOÚ Brno, ČR 2;  Ústav nukleární medicíny, 1. lékařské fakulty UK a Všeobecné fakultní nemocnice v Praze, ČR 3;  Interní hematologická a onkologická klinika, LF MU a FN Brno, ČR 4;  I. interní klinika – klinika hematologie, 1. lékařské fakulty UK a Všeobecné fakultní nemocnice v Praze, ČR 5
Published in the journal: NuklMed 2018;7:50-52
Category: Original Article

Summary

Introduction:

Erdheim-Chester disease (ECD) is a rare unit of histiocytic diseases. The goal of our work was to assess 18F-FDG PET/CT presentation of this disease in patients from the Czech Republic.

Methods:

We analyzed overall 44 18F-FDG PET/CT examinations in 6 patients with this disease. We assessed 18F-FDG accumulation in staging examinations of these 6 patients at usual localizations, i.e. bones, brain, orbit, paranasal sinuses, periaortal space, heart, lungs, perirenal space and skin.

Results:

Bone 18F-FDG accumulation was detected in all patients; in 5 mostly in lower extremities. Maxillar sinuses were involved in 5/6 patients. Vascular and perirenal involvement was detected in 4/6 patients. Two patients had involved skin and hypophysis, one patient also orbits and heart. Lung involvement was not detected in any patient.

Conclusions:

18F-FDG avid involvement of skeleton was the main and regular characteristic of PET/CT presentation of Erdheim-Chester disease. Also other localizations of 18F-FDG avid involvement (cardiovascular, CNS, paranasal sinuses, orbitis, skin, perirenal space) confirm known observations in ECD.

Key Words:

18F-FDG, PET/CT, Erdheim-Chester disease

Zdroje
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Nuclear Medicine

Číslo 3
2018 Číslo 3
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