Attenuation correction of myocardial perfusion imaging on CZT SPECT camera using external CT including ECG-gated CT coronary artery calcium score
Authors:
M. Kamínek; P. Karhan
Authors‘ workplace:
Klinika nukleární medicíny LF a FZV UP a FN Olomouc, ČR
Published in:
NuklMed 2025;14:2-6
Category:
Review Article
Overview
To improve the accuracy of myocardial perfusion imaging, it is necessary to acquire the additional study in a changed body position, or to use a CT attenuation correction (AC). AC can be technically easil performed on a hybrid SPECT/CT camera. For AC on SPECT only camera, typically cardiac Cadmium Zinc Telluride (CZT) camera, we can use an external CT. Moreover, even ECG-gated CT coronary artery calcium scoring can be used for AC. The aim of our study is to present our experience with the fusion of SPECT and CT for AC on CZT camera.
Keywords:
attenuation correction – external CT – coronary artery calcium scoring – CZT SPECT camera
Sources
- Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J 2024;45:3415-3537
- Neumann FJ, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2019;40:87-165
- Schepis T, Gaemperli O, Koepfli P, et al. Added value of coronary artery calcium score as an adjunct to gated SPECT for the evaluation of coronary artery disease in an intermediate risk population. J Nucl Med 2007;48:1424-1430
- Havel M, Kamínek M, Metelková M, et al. Combination of myocardial perfusion imaging, left ventricle function parameters and coronary artery calcium score in risk evaluation in patients with diabetes mellitus. Hell J Nucl Med 2022;25: 227-234
- Gimelli A, Achenbach S, Buechel RR, et al. Strategies for radiation dose reduction in nuclear cardiology and cardiac computed tomography imaging: a report from the European Association of Cardiovascular Imaging (EACVI), the Cardiovascular Committee of European Association of Nuclear Medicine (EANM), and the European Society of Cardiovascular Radiology (ESCR). Eur Heart J 2018;39:286-296
- Einstein AJ, Johnson LL, Bokhari S, et al. Agreement of visual estimation of coronary artery calcium from low-dose CT attenuation correction scans in hybrid PET/CT and SPECT/CT with standard Agatston score. J Am Coll Cardiol 2010;56:1914-1921
- Kincl V, Kamínek M, Vašina J, et al. Feasibility of ultra low-dose thallium stress-redistribution protocol including prone imaging in obese patients using CZT camera. International Journal of Cardiovascular Imaging 2016;32:1463-1469
- Bednárová V, Kincl V, Kamínek M, et al. The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT. Int J Cardiovasc Imaging 2019;35:1163-1167 doi: 10.1007/s10554-019-01535-7.
- Agostini D, Roule V, Nganoa C, et al. First validation of myocardial flow reserve assessed by dynamic 99mTc-sestamibi CZT-SPECT camera: head to head comparison with 15O-water PET and fractional flow reserve in patients with suspected coronary artery disease. The WATERDAY study. Eur J Nucl Med Mol Imaging 2018;45:1079-1090
- Nkoulou R, Fuchs TA, Pazhenkottil AP, et al. Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head-to-Head Comparison with 13N-Ammonia PET. J Nucl Med 2016;57:1887-1892
- Giubbini R, Bertoli M, Durmo R, et al. Comparison between N13NH3-PET and 99mTc-Tetrofosmin-CZT SPECT in the evaluation of absolute myocardial blood flow and flow reserve. J Nucl Cardiol. Epub 2019 Nov 14. doi: 10.1007/s12350-019-01939-x.
- Kamínek M, Metelková I, Henzlová L. Dynamický SPECT a kvantifikace coronary flow reserve na CZT kameře. Nukl Med 2021;10:58-62
- Caobelli F, Dweck MR, Albano D, et al. Hybrid cardiovascular imaging. A clinical consensus statement of the european association of nuclear medicine (EANM) and the european association of cardiovascular imaging (EACVI) of the ESC. Eur J Nucl Med Mol Imaging 2025; 52:1095–1118
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Nuclear Medicine
2025 Issue 1
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