Manifestation of IgG4 Associated Disease in the Head and Neck Region
Authors:
J. Hybášková 1; Karol Zeleník 1,2
; O. Urban 2,3; P. Vítek 2,4; P. Matoušek 1,2
; Pavel Komínek 1,2
Authors place of work:
Klinika otorinolaryngologie a chirurgie hlavy a krku, Fakultní nemocnice Ostrava, přednosta prof. MUDr. P. Komínek, Ph. D., MBA
1; Lékařská fakulta, Ostravská univerzita, vedoucí katedry prof. MUDr. P. Komínek, Ph. D., MBA
2; Centrum péče o zažívací trakt, Vítkovická nemocnice, Ostrava, primář MUDr. O. Urban, Ph. D.
3; Interní oddělení, Nemocnice ve Frýdku-Místku, primář MUDr. P. Vítek, Ph. D.
4
Published in the journal:
Otorinolaryngol Foniatr, 64, 2015, No. 3, pp. 163-167.
Category:
Review Article
Summary
Immunoglobulin G4 – related disease (IgG4-RD) is a rare systemic fibro-inflammatory disorder. Although patients have been described more then 100 years ago, the systemic nature of this disease has been recognized in the 21st century only. IgG4-RD can affect any organ such as salivary glands, orbits, retroperitoneum and many others. Recent research enabled a clear clinical and histopathological description of IgG4-RD. Typically, lymphoplasmacellular inflammation, storiform fibrosis and obliterative flebitis, are found in IgG4-RD biopsies. Elevated serum IgG4 levels are found in many but not all patiens. Treatment is based on clinical experience. Glucocorticoids are the mainstay of therapy, although adjunctive immunosuppressive agents are used in relapsing patient.
Keywords:
IgG4-RD, immunoglobulin 4, storiform fibrosis, lymphoplasmacytis inflammations
Zdroje
1. Alamino, P. R., Espinoza, L. R., Zea, A. H.: The great mimicker: IgG4-related disease. Clin. Rheumatol., 32, 2013, s. 1267-1273.
2. Chány, S. Y., Keogh, K. A., Lewis, J. E., Ryu, J. H., Cornell, L. D., Garrit, J. A., Yi, S. E.: IgG4-positive plasma cells in granulomatosis with polyangiitis (Wegener´s): a clinicopathologic and immunohistochemical study on 43 granulomatosis with polyangiitis and 20 control cases. Human Pahology, 44, 2013, s. 2432-2437.
3. Japanese study group of IgG4-related ophtalmic disease: A prevalence study of IgG4-related ophthalmic disease in Japan. Jpn. J. Ophthalmol., 57, 2013, s. 573-579.
4. Katsura, M., Mori, H., Kunimatsu, A., Sasaki,H., Abe, O., Machina, T., Ohtomo, K.: Radiological features of IgG4-related disease in the head, neck, and brain. Neuroradiology, 54, 2012, s. 873-882.
5. Laco, J., Kamarádová, K., Mottl, R., Mottlová, A., Doležalová, H., Tuček, L., Žatečková, K., Slezák, R.: Plasma cell granuloma of the oral cavity – a mucosal manifestation of imunoglobulin G4-related disease or a mimic?. The European Journal of Pathology, 466, 2015, 3, s. 255-263.
6. Laco, J., Ryška, A., Čelakovký, P., Doležalová, H., Mottl, R., Tuček, L.: Chronic sclerosing sialadenitis as one of the imunoglobulin G4-related disease: a clinicopathological study of six cases from Central Europe. Histopatology, 58, 2011, s. 1157-1163.
7. Mahajan, V. S., Matoo, H., Deshpande, V., Pillai, S. S., Stone, J. H.: IgG4-related disease. Ann. Rev. Pathol., 2014, 9, s. 315-347.
8. Pieringer, H., Parter, I., Wöhrer, A., Reis, P., Oppl, B., Zwerina, J.: IgG4-related disease: an orphan disease with many faces. Orphanet Journal of Rare Disease, 2014, 9, s. 110-114.
9. Saito, Y., Kagami, S., Kawashima, S., Takahashi, K., Ikeda, K., Virose, K., Oshitari, T., Yamamoto, S., Okamoto, Y., Nakajima, H.: Role sof CRTH2+ CD4+ T Cells in Immunoglobulin G4-Related Lacrimal Gland Enlargement. Int. Arch.Allergy Immunol., 158, 2012, s. 42-46.
10. Sato, Y., Takeuchi, M., Takata, K., Ohno, K., Iwaki, N., Orita, Y., Goto, N. I, Hida, A., Iwamoto, T., Asano, N., Ito, T., Hanakawa, H., Yanai, H., Yoshino T.: Clinicopathologic analysis of IgG4-related skin disease. Modern Pathology, 26, 2013, s. 523-532.
11. Smith, B., Carroll, B. M.: Persistent lymphadenopathy due to IgG4-related disease. Case Report in Immunology, 2012, s. 1-4.
12. Sogabe, Y., Miyatani, K., Goto, R., Ishii, G., Ohshima, K., Sato, Y.: Pathological findings of infraorbital nerve enlargement in IgG4-related ophtalmic disease. Jpn. . Ophthalmol., 56, 2012, s. 511-514.
13. Yamamoto, M., Tabela, T., Naishiro, Y., Tajina, H., Ishigami, K., Shimizu, Y., Obara, M., Sužuji, Ch., Yamashita, K., Yamamoto, H., Hayashi, T., Sasaki, S., Sugaya, T., Ishida, T., Takano, K., Himi, T., Sužuji, Y., Nishimoto, N., Honda, S., Takahashi, H., Omak, K., Shinomura, Y.: Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Mod. Rheumatol., 22, 2012, s. 419-424.
14. Umehara, H., Okazaki, K., Masaki, Y., Kawano, M., Ymamoto, M., Saeki, T., Matsui, S., Toshibo, T., Nakanuta, S., Kawa, S., Hamano, H., Kamisawa, T., Shimosegawa, T., Shimatsu, A., Nakanuta, S., Ito, T., Notohara, K., Sumida, T., Tahala, Y., Mimori, T., Chiba, T., Mishima, M., Hibi, T., Tsubouchi, H., Inui, K., Ohar, H.: Comprehensive diagnostic kriteria for IgG4-related dinase (IgG4-RD). Mod. Rheumatol., 22, 2012, s. 21-30.
15. Umehara, H., Okazaki, K., Masaki, Y., Kawano, M., Yamamoto, M., Saeki, T., Matsui, S., Sumida, T., Mimori, T., Tahala, Y., Tsubota, K., Toshibo,T., Kawa, S., Sužuji, R., Raketami, T., Tomosugi, N., Kurose, N., Ishigaki, Y., Szuji, A., Kojima, M., Nakanuta, S., Inoue, D.: Research program for intractable disease by ministry of health, labor and welfare (MHLW) Japan G4 team.: A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details. Mod. Rheumatol., 22, 2012, s. 1-14.
Štítky
Audiology Paediatric ENT ENT (Otorhinolaryngology)Článok vyšiel v časopise
Otorhinolaryngology and Phoniatrics
2015 Číslo 3
Najčítanejšie v tomto čísle
- Phoniatric Care for Patients with Temporary or Permanent Vocal Cord Paralysis Following Operations on the Thyroid Gland
- Juvenile Angiofibroma of Nasopharynx
- Sialoendoscopy in Diagnostics and Therapy of Submandibular Sialolithiasis
- Revision Septorhinoplasties