Influence of hormone replacement therapy on waist-to-hip ratio

Česká verzia

Authors: MUDr. Tomáš Fait
Authors place of work: 1. LF UK a VFN, Praha ; Gynekologicko-porodnická klinika
Published in the journal: Prakt Gyn 2005; 9(2): 21-22

Summary

Metabolic changes in postmenopause include the preference of visceral body fat storage. It is a risk factor for cardiovascular diseases and breast carcinoma. We try to confirm the ability of hormonal therapy (estradiol valerate 2 mg + dienogest 2 mg) to protect from visceral body fat distribution. Group of 933 postmenopausal women were observed in opened prospective multicentric noncontroled study. The duration of study was from 3 to 9 month. Waist-to-hip ratio (WHR) decreased in 418 patients. 241 patients showed no changes of WHR. We observed the lowering or the preservation of WHR in 70.6 % of patients.

Key words:
waist-to-hip ratio – obesity – hormonal replacement therapy

Zdroje

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