Immunophenotyping of childhood leukaemias
Imunofenotypizace dětských leukemií
Imunofenotypizace je již dnes standardní metodou v diagnostice hemato-onkologických onemocnění. V současné době zažíváme rozvoj mnohobarevné průtokové cytometrie, jak ve výzkumu, tak i v klinické diagnostice. Práce shrnuje diagnostiku a sledování akutní lymfoblastické leukemie pomocí průtokové cytometrie.
Klíčová slova:
imunofenotypizace, mnohobarevná průtoková cytometrie, akutní leukemie, expresní profilování, minimální reziduální nemoc
Authors:
T. Kalina 1,2,3; E. Mejstříková 1,2,3; M. Vášková 1,2,3; O. Hrušák 1,2,3
Authors‘ workplace:
Ústav imunologie, 2Klinika dětské hematologie a onkologie UK 2. LF a FN Motol, 3CLIP Childhood Leukemia
Investigation Prague
1
Published in:
Transfuze Hematol. dnes,12, 2006, No. 1, p. 20-25.
Category:
Comprehensive Reports, Original Papers, Case Reports
Overview
Immunophenotyping is a standard method used in diagnostics of hematological malignancies. Progress in number of multicolour cytometry as well as new targets identified by genomics bring new possibilities in research and diagnostics. These aspects are summarized in the article.
Key words:
immunophenotyping, multicolour flow cytometry, acute leukaemia, expression profiling, minimal residual disease
Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
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