Disseminated carcinomatosis of the bone marrow from pancreatic cancer: a case report

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Background:
Most cases of disseminated carcinomatosis of the bone marrow (DCBM) arise from gastric cancer. DCBM from pancreatic cancer is very rare. We herein present a case of DCBM from pancreatic cancer.

Case presentation:
A 57-year-old man was referred to our hospital for severe lumbago. Laboratory data indicated that he suffered from disseminated intravascular coagulation (DIC). Non-contrast abdominal computed tomography (CT) revealed multiple bone masses but no other abnormal findings. Left iliac bone marrow biopsy revealed poorly differentiated adenocarcinoma cells. Positron emission tomography (PET)-CT showed diffuse abnormal uptake in the bones and tail of the pancreas. Contrast whole-body CT showed a tumor measuring approximately 28 mm in diameter with poor enhancement in the tail of the pancreas. The patient’s final diagnosis was pancreatic cancer located in the tail of the pancreas with diffuse bone metastases and DIC. His DCBM was thus believed to originate from the pancreatic cancer. He succumbed to the disease approximately 2 months after admission to our hospital.

Conclusion:
We herein describe a case of pancreatic cancer located in the tail of the pancreas with diffuse bone metastases and DIC, which, in our case, was DCBM. Therefore, in cases of DCBM with an unknown primary tumor, pancreatic cancer should be considered during differential diagnosis.

Keywords:
Disseminated carcinomatosis of the bone marrow, Disseminated intravascular coagulation, Diffuse bone metastases, Pancreatic cancer

Autoři: Hiroki Namikawa ¹; Yasuhiko Takemoto ^1*; Ayako Makuuchi ¹; Masanori Kobayashi ¹; Shigeki Kinuhata ¹; Mina Morimura ¹; Takashi Ikebe ^1,2; Hiromu Tanaka ³; Taichi Shuto ¹
Působiště autorů: Department of Medical Education and General Practice, Osaka City University, Graduate School of Medicine, 1-4- , Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. ¹; Department of Emergency and General Practice, Higashi Sumiyoshi Morimoto Hospital, -2-66, Takaai, Higashisumiyoshi-ku, Osaka 546-0014, Japan. ²; Department of Palliative Care, Higashi Sumiyoshi Morimoto Hospital, 3-2-66, Takaai, Higashisumiyoshi-ku, Osaka 546-0014, Japan. ³
Vyšlo v časopise: BMC Cancer 2016, 16:801
Kategorie: Case report
prolekare.web.journal.doi_sk: https://doi.org/10.1186/s12885-016-2849-1

© 2016 The Author(s).

Open access
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
The electronic version of this article is the complete one and can be found online at: http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2849-1

Souhrn

Keywords:
Disseminated carcinomatosis of the bone marrow, Disseminated intravascular coagulation, Diffuse bone metastases, Pancreatic cancer

Zdroje

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