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Current practices in cancer pain management in Asia: a survey of patients and physicians across 10 countries


Abstract:
In order to implement more effective policies for cancer pain management, a better understanding of current practices is needed. Physicians managing cancer pain and patients experiencing cancer pain were randomly surveyed across 10 Asian countries to assess attitudes and perceptions toward cancer pain management. A total of 463 physicians (77.3% oncologists) with a median experience of 13 years were included. Medical school training on opioid use was considered inadequate by 30.5% of physicians and 55.9% indicated ≤10 h of continuing medical education (CME). Of the 1190 patients included, 1026 reported moderate-to-severe pain (median duration, 12 months). Discordance was observed between physician and patient outcomes on pain assessment with 88.3% of physicians reporting pain quantification, while 49.5% of patients claimed that no scale was used. Inadequate assessment of pain was recognized as a barrier to therapy optimization by 49.7% of physicians. Additional barriers identified were patients' reluctance owing to fear of addiction (67.2%) and adverse events (65.0%), patients' reluctance to report pain (52.5%), excessive regulations (48.0%) and reluctance to prescribe opioids (42.8%). Opioid use was confirmed only in 53.2% (286/538) of patients remembering their medication. Pain affected the activities of daily living for 81.3% of patients. These findings highlight the need for better training and CME opportunities for cancer pain management in Asia. Collaborative efforts between physicians, patients, policy makers, and related parties may assist in overcoming the barriers identified. Addressing the opioid stigma and enhancing awareness is vital to improving current standards of patient care.

Keywords:
Cancer pain; pain management survey


Autoři: The Acheon Working Group;  Yong-Chul Kim 1,*;  Jin Seok Ahn 2;  Maria Minerva P. Calimag 3;  Ta Chung Chao 4,5;  Kok Yuen Ho 6;  Lye Mun Tho 7;  Zhong-Jun Xia 8;  Lois Ward 9;  Hanlim Moon 10;  Abhishek Bhagat 10
Působiště autorů: Department of Anesthesiology and Pain Medicine, Seoul National University School of Medicine, Seoul, Korea 1;  Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2;  Departments of Pharmacology, Clinical Epidemiology and Anesthesiology, University of Santo Tomas Faculty of Medicine and Surgery and the UST Hospital, Manila, Philippines 3;  Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, China 4;  Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, China 5;  Pain Management Service, Raffles Hospital, Singapore, Singapore 6;  Department of Clinical Oncology, Beacon International Specialist Centre, Selangor, Malaysia 7;  Sun Yat-Sen University Cancer Center, Guangzhou, China 8;  Mundipharma Research Ltd, Cambridge, United Kingdom 9;  Mundipharma Pte Ltd, Singapore, Singapore 10
Vyšlo v časopise: Cancer Medicine 2015; 4(8)
Kategorie: Original Research
prolekare.web.journal.doi_sk: https://doi.org/10.1002/cam4.471

© 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
© 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Souhrn

Abstract:
In order to implement more effective policies for cancer pain management, a better understanding of current practices is needed. Physicians managing cancer pain and patients experiencing cancer pain were randomly surveyed across 10 Asian countries to assess attitudes and perceptions toward cancer pain management. A total of 463 physicians (77.3% oncologists) with a median experience of 13 years were included. Medical school training on opioid use was considered inadequate by 30.5% of physicians and 55.9% indicated ≤10 h of continuing medical education (CME). Of the 1190 patients included, 1026 reported moderate-to-severe pain (median duration, 12 months). Discordance was observed between physician and patient outcomes on pain assessment with 88.3% of physicians reporting pain quantification, while 49.5% of patients claimed that no scale was used. Inadequate assessment of pain was recognized as a barrier to therapy optimization by 49.7% of physicians. Additional barriers identified were patients' reluctance owing to fear of addiction (67.2%) and adverse events (65.0%), patients' reluctance to report pain (52.5%), excessive regulations (48.0%) and reluctance to prescribe opioids (42.8%). Opioid use was confirmed only in 53.2% (286/538) of patients remembering their medication. Pain affected the activities of daily living for 81.3% of patients. These findings highlight the need for better training and CME opportunities for cancer pain management in Asia. Collaborative efforts between physicians, patients, policy makers, and related parties may assist in overcoming the barriers identified. Addressing the opioid stigma and enhancing awareness is vital to improving current standards of patient care.

Keywords:
Cancer pain; pain management survey


Zdroje

1. Ferlay, J., H. R. Shin, F. Bray, D. Forman, C. Mathers, and D. M. Parkin. 2010. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127:2893–2917.

2. van den Beuken-van Everdingen, M. H., J. M. de Rijke, A. G. Kessels, H. C. Schouten, M. van Kleef, and J. Patijn. 2007. Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann. Oncol.18:1437–1449.

3. Deandrea, S., M. Montanari, L. Moja, and G. Apolone. 2008. Prevalence of undertreatment in cancer pain. A review of published literature. Ann. Oncol. 19:1985–1991.

4. Law, S. C., Y. O. Ahn, Y. B. Xiang, et al. 2010. Cancer survival in Africa, Asia, and Central America: a population-based study. Lancet Oncol. 11:165–173.

5. Sankaranarayanan, R., R. Swaminathan, H. Brenner, K. Chen, K. S. Chia, J. G. Chen, et al. 2011. Cancer survival in Africa, Asia, the Caribbean and Central America. IARC scientific Publications No. 162. International Agency for Research on Cancer, Lyon, France.

6. Cleary, J., M. Silbermann, W. Scholten, L. Radbruch, J. Torode, and N. I. Cherny. 2013. Formulary availability and regulatory barriers to accessibility of opioids for cancer pain in Asia: a report from the Global Opioid Policy Initiative (GOPI). Ann. Oncol. 24(Suppl. 11):24–32.

7. World Health Organization. 2002. National cancer control programmes: policies and managerial guidelines.2nd ed. World Health Organization, Geneva, Switzerland.

8. Benedetti, C., C. Brock, C. Cleeland; National Comprehensive Cancer Network, et al. 2000. NCCN practice guidelines for cancer pain. Oncology 14:135–150.

9. Kwon, J. H. 2014. Overcoming barriers in cancer pain management. J. Clin. Oncol. 32:1727–1733.

10. De Leon, J. R., and E. Espinosa. 2008. Pattern of pain management practices of Filipino surgeons. Oncology74:40–45.

11. Yun, Y. H., S. M. Park, K. Lee, Y. J. Chang, D. S. Heo, S.-Y. Kim, et al. 2005. Predictors of prescription of morphine for severe cancer pain by physicians in Korea. Ann. Oncol. 16:966–971.

12. Lim, R. 2008. Improving cancer pain management in Malaysia. Oncology 74:24–34.

13. Hum, A., A. Lee, and W. H. Yaw. 2009. Cancer pain—progress and ongoing issues in Singapore. Pain Res. Manag. 14:300–361.

14. ICC European Society for Opinion and Market Research international code on market and social research, 2007. Available at: http://www.esomar.org/uploads/public/knowledge-and-standards/codes-and-guidelines/ICCESOMAR_Code_English_.pdf (accessed 25 December 2014).

15. Javier, F. O., and M. P. Calimag. 2007. Opioid use in the Philippines—20 years after the introduction of the WHO analgesic ladder. Eur. J. Pain 1(Suppl. 1):19–22.

16. Nagaviroj, K., and D. Jaturapatporn. 2009. Cancer pain—progress and ongoing issues in Thailand. Pain Res. Manag. 14:361–362.

17. Hseih, R. K. 2005. Pain control in Taiwanese patients with cancer: a multicentre, patient-oriented survey. J. Formos. Med. Assoc. 104:913–919.

18. Yanjun, S., W. Changli, W. Ling, J. C. Woo, K. Sabrina, L. Chang, et al. 2010. A survey on physician knowledge and attitudes towards clinical use of morphine for cancer pain treatment in China. Support. Care Cancer18:1455–1460.

19. Jeon, Y. S., H. K. Kim, C. S. Cleeland and X. S. Wang. 2007. Clinicians' practice and attitudes toward cancer pain management in Korea. Support. Care Cancer 15:463–469.

20. Srisawang, P., M. Harun-Or-Rashid, T. Hirosawa, and J. Sakamoto. 2013. Knowledge, attitudes, and barriers of physicians, policy makers/regulators use of opioids for cancer pain management in Thailand. Nagoya J. Med. Sci. 75:201–212.

21. Liao, Z., J. Hao, Y. Guo, C. Reyes-Gibby, and H. Guo. 2013. Assessment of cancer pain management knowledge in southwest China: a survey of 259 physicians from small city and county hospitals. J. Palliat. Med. 16:692–695.

22. Chen, C. H., S. T. Tang, and C. H. Chen. 2012. Meta-analysis of cultural differences in Western and Asian patient-perceived barriers to managing cancer pain. Palliat. Med. 26:206–221.

23. Im, E. O., Y. Liu, Y. H. Kim, and W. Chee. 2008. Asian American cancer patients' pain experience. Cancer Nurs.31:E17–E23.

24. Joranson, D. E., K. M. Ryan, A. M. Gilson, and J. L. Dahl. 2000. Trends in medical use and abuse of opioid analgesics. JAMA 283:1710–1714.

25. Portenoy, R. K., J. T. Farrar, M. M. Backonja, C. S. Cleeland, K. Yang, and M. Friedman. 2007. Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry study. Clin. J. Pain 23:287–299.

26. Tse, M. M., A. C. Wong, H. N. Ng, H. Y. Lee, M. H. Chong, and W. Y. Leung. 2012. The effect of a pain management program on patients with cancer pain. Cancer Nurs. 35:438–446.

27. Lin, C. C., P. L. Chou, S. L. Wu, Y. C. Chang, and Y. L. Lai. 2006. Long-term effectiveness of a patient and family pain education program on overcoming barriers to management of cancer pain. Pain 122:271–281.

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Onkológia

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Cancer Medicine

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2015 Číslo 8
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