Machine learning using speech utterances for parkinson disease detection

English version

Autoři: Ondřej Klempíř; Radim Krupička
Působiště autorů: Department of Biomedical Informatics, Faculty of Biomedical Engineering, Czech Technical University in Prague, Kladno, Czech Republic
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 2, 2018, 48, 66-71
Kategorie: Original research

Souhrn

Pathophysiological recordings of patients measured from various testing methods are frequently used in the medical field for determining symptoms as well as for probability prediction for selected diseases. There are numerous symptoms among the Parkinson’s disease (PD) population, however changes in speech and articulation are potentially the most significant biomarker. This article is focused on PD diagnosis classification based on their speech signals using pattern recognition methods (AdaBoost, Bagged trees, Quadratic SVM and k-NN). The dataset investigated in the article consists of 30 PD and 30 healthy controls (HC) individuals voice measurements, with each individual being represented with 2 recordings within the dataset. Training signals for PD and HC underwent an extraction of relatively well-discriminating features relating to energy and spectral speech properties. Model implementations included a 5-fold cross validation. The accuracy of values obtained by employing the models was calculated using a confusion matrix. The average value of the overall accuracy = 82.3% and averaged AUC = 0.88 (min. AUC = 0.86) on the available data.

Keywords:

Parkinson's disease, speech, machine learning, digital biomarker, classification

Zdroje

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