Public Service by a Selfish Gene: A Domesticated Transposase Antagonizes Polycomb Function

1. Liang SC, Hartwig B, Perera P, Mora-Garcia S, de Leau E, Thornton H, et al. Kicking against the PRCs—A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet. 2015;11(12):e1005660. doi: 10.1371/journal.pgen.1005660 26642436

2. Zhang X, Clarenz O, Cokus S, Bernatavichute YV, Pellegrini M, Goodrich J, et al. Whole-genome analysis of histone H3 lysine 27 trimethylation in Arabidopsis. PLoS Biol. 2007;5(5):e129. 17439305

3. Hartwig B, James GV, Konrad K, Schneeberger K, Turck F. Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks. Plant physiology. 2012;160(2):591–600. doi: 10.1104/pp.112.200311 22837357

4. Walker EL, Eggleston WB, Demopulos D, Kermicle J, Dellaporta SL. Insertions of a novel class of transposable elements with a strong target site preference at the r locus of maize. Genetics. 1997;146(2):681–93. 9178016

5. Zhang X, Feschotte C, Zhang Q, Jiang N, Eggleston WB, Wessler SR. P instability factor: an active maize transposon system associated with the amplification of Tourist-like MITEs and a new superfamily of transposases. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(22):12572–7. 11675493

6. Kapitonov VV, Jurka J. Molecular paleontology of transposable elements from Arabidopsis thaliana. Genetica. 1999;107(1–3):27–37. 10952195

7. Zhang X, Jiang N, Feschotte C, Wessler SR. PIF- and Pong-like transposable elements: distribution, evolution and relationship with Tourist-like miniature inverted-repeat transposable elements. Genetics. 2004;166(2):971–86. 15020481

8. Yang G, Zhang F, Hancock CN, Wessler SR. Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 2007;104(26):10962–7. 17578919

9. Sinzelle L, Kapitonov VV, Grzela DP, Jursch T, Jurka J, Izsvak Z, et al. Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes. Proceedings of the National Academy of Sciences of the United States of America. 2008;105(12):4715–20. doi: 10.1073/pnas.0707746105 18339812

10. Sinzelle L, Izsvak Z, Ivics Z. Molecular domestication of transposable elements: from detrimental parasites to useful host genes. Cellular and molecular life sciences: CMLS. 2009;66(6):1073–93. doi: 10.1007/s00018-009-8376-3 19132291

11. Feschotte C, Pritham EJ. DNA transposons and the evolution of eukaryotic genomes. Annual review of genetics. 2007;41:331–68. 18076328

12. Cordaux R, Udit S, Batzer MA, Feschotte C. Birth of a chimeric primate gene by capture of the transposase gene from a mobile element. Proceedings of the National Academy of Sciences of the United States of America. 2006;103(21):8101–6. 16672366

13. Hromas R, Wray J, Lee SH, Martinez L, Farrington J, Corwin LK, et al. The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining. DNA repair. 2008;7(12):1927–37. doi: 10.1016/j.dnarep.2008.08.002 18773976

14. Bundock P, Hooykaas P. An Arabidopsis hAT-like transposase is essential for plant development. Nature. 2005;436(7048):282–4. 16015335

15. Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H. Transposase-derived transcription factors regulate light signaling in Arabidopsis. Science. 2007;318(5854):1302–5. 18033885

16. Deleris A, Stroud H, Bernatavichute Y, Johnson E, Klein G, Schubert D, et al. Loss of the DNA methyltransferase MET1 Induces H3K9 hypermethylation at PcG target genes and redistribution of H3K27 trimethylation to transposons in Arabidopsis thaliana. PLoS Genet. 2012;8(11):e1003062. doi: 10.1371/journal.pgen.1003062 23209430