Reactive Oxygen Species: From Harmful Molecules to Fine-Tuning Regulators of Stem Cell Niche Maintenance

1. Theopold U (2009) Developmental biology: A bad boy comes good. Nature 461: 486–487. doi: 10.1038/461486a 19779443

2. Bigarella CL, Liang R, Ghaffari S (2014) Stem cells and the impact of ROS signaling. Development 141: 4206–4218. doi: 10.1242/dev.107086 25371358

3. Ludin A, Gur-Cohen S, Golan K, Kaufmann KB, Itkin T, et al. (2014) Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment. Antioxid Redox Signal 21: 1605–1619. doi: 10.1089/ars.2014.5941 24762207

4. Jiang K, Meng YL, Feldman LJ (2003) Quiescent center formation in maize roots is associated with an auxin-regulated oxidizing environment. Development 130: 1429–1438. 12588857

5. Dunand C, Crevecoeur M, Penel C (2007) Distribution of superoxide and hydrogen peroxide in Arabidopsis root and their influence on root development: possible interaction with peroxidases. New Phytol 174: 332–341. 17388896

6. Tsukagoshi H, Busch W, Benfey PN (2010) Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root. Cell 143: 606–616. doi: 10.1016/j.cell.2010.10.020 21074051

7. Yu Q, Tian H, Yue K, Liu J, Zhang B, et al. (2016) A P-loop NTPase regulates quiescent center cell division and distal stem cell identity through the regulation of ROS homeostasis in Arabidopsis root. PLoS Genet 12(9): e1006175. doi: 10.1371/journal.pgen.1006175

8. Lee Y, Lee WS, Kim S-H (2012) Hormonal regulation of stem cell maintenance in roots. Journal of Experimental Botany;64(5):1153–65 doi: 10.1093/jxb/ers331 23183258

9. Ding Z, Friml J (2010) Auxin regulates distal stem cell differentiation in Arabidopsis roots. Proceedings of the National Academy of Sciences of the United States of America 107: 12046–12051. doi: 10.1073/pnas.1000672107 20543136

10. Yang L, Zhang J, He J, Qin Y, Hua D, et al. (2014) ABA-mediated ROS in mitochondria regulate root meristem activity by controlling PLETHORA expression in Arabidopsis. PLoS Genet 10: e1004791. doi: 10.1371/journal.pgen.1004791 25522358

11. Kerchev PI, De Clercq I, Denecker J, Muhlenbock P, Kumpf R, et al. (2014) Mitochondrial perturbation negatively affects auxin signaling. Mol Plant 7: 1138–1150. doi: 10.1093/mp/ssu071 24903751

12. Silva-Navas J, Moreno-Risueno MA, Manzano C, Pallero-Baena M, Navarro-Neila S, et al. (2015) D-Root: a system to cultivate plants with the root in darkness or under different light conditions. The Plant Journal 84: 244–255. doi: 10.1111/tpj.12998 26312572

13. Silva-Navas J, Moreno-Risueno MA, Manzano C, Téllez-Robledo B, Navarro-Neila S, et al. (2016) Flavonols mediate root phototropism and growth through regulation of Proliferation to-Differentiation Transition. Plant Cell 28: 1372–1387. doi: 10.1105/tpc.15.00857 26628743