PRRG4 function reveals that Robo trafficking is evolutionarily conserved

1. Abrahams BS, Geschwind DH. Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet. 2008;9: 341–355. doi: 10.1038/nrg2346 18414403

2. Geschwind DH, Levitt P. Autism spectrum disorders: developmental disconnection syndromes. Current Opinion in Neurobiology. 2007;17: 103–111. doi: 10.1016/j.conb.2007.01.009 17275283

3. Justice ED, Barnum SJ, Kidd T. The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene. PLoS Genet. 2017.

4. Dickson BJ, Gilestro GF. Regulation of Commissural Axon Pathfinding by Slit and its Robo Receptors. Annu Rev Cell Dev Biol. 2006;22: 651–675. doi: 10.1146/annurev.cellbio.21.090704.151234 17029581

5. Kidd T, Brose K, Mitchell KJ, Fetter RD, Tessier-Lavigne M, Goodman CS, et al. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell. 1998;92: 205–215. 9458045

6. Keleman K, Rajagopalan S, Cleppien D, Teis D, Paiha K, Huber LA, et al. Comm sorts robo to control axon guidance at the Drosophila midline. Cell. 2002;110: 415–427. 12202032

7. Myat A, Henry P, McCabe V, Flintoft L, Rotin D, Tear G. Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor. Neuron. Elsevier; 2002;35: 447–459. doi: 10.1016/S0896-6273(02)00795-X

8. Friocourt F, Chédotal A. The Robo3 receptor, a key player in the development, evolution, and function of commissural systems. Devel Neurobio. 2017. doi: 10.1002/dneu.22478 28033646

9. Gilestro GF. Redundant Mechanisms for Regulation of Midline Crossing in Drosophila. Schweisguth F, editor. PLoS ONE. 2008;3: e3798–11. doi: 10.1371/journal.pone.0003798 19030109

10. Kidd T, Russell C, Goodman CS, Tear G. Dosage-sensitive and complementary functions of roundabout and commissureless control axon crossing of the CNS midline. Neuron. 1998;20: 25–33. 9459439

11. Blockus H, Chédotal A. The multifaceted roles of Slits and Robos in cortical circuits: from proliferation to axon guidance and neurological diseases. Current Opinion in Neurobiology. 2014;27: 82–88. doi: 10.1016/j.conb.2014.03.003 24698714