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Living Alone and Alcohol-Related Mortality: A Population-Based Cohort Study from Finland


Background:
Social isolation and living alone are increasingly common in industrialised countries. However, few studies have investigated the potential public health implications of this trend. We estimated the relative risk of death from alcohol-related causes among individuals living alone and determined whether this risk changed after a large reduction in alcohol prices.

Methods and Findings:
We conducted a population-based natural experimental study of a change in the price of alcohol that occurred because of new laws enacted in Finland in January and March of 2004, utilising national registers. The data are based on an 11% sample of the Finnish population aged 15–79 y supplemented with an oversample of deaths. The oversample covered 80% of all deaths during the periods January 1, 2000–December 31, 2003 (the four years immediately before the price reduction of alcohol), and January 1, 2004–December 31, 2007 (the four years immediately after the price reduction). Alcohol-related mortality was defined using both underlying and contributory causes of death. During the 8-y follow-up about 18,200 persons died due to alcohol-related causes. Among married or cohabiting people the increase in alcohol-related mortality was small or non-existing between the periods 2000–2003 and 2004–2007, whereas for those living alone, this increase was substantial, especially in men and women aged 50–69 y. For liver disease in men, the most common fatal alcohol-related disease, the age-adjusted risk ratio associated with living alone was 3.7 (95% confidence interval 3.3, 4.1) before and 4.9 (95% CI 4.4, 5.4) after the price reduction (p<0.001 for difference in risk ratios). In women, the corresponding risk ratios were 1.7 (95% CI 1.4, 2.1) and 2.4 (95% CI 2.0, 2.9), respectively (p ≤ 0.01). Living alone was also associated with other mortality from alcohol-related diseases (range of risk ratios 2.3 to 8.0) as well as deaths from accidents and violence with alcohol as a contributing cause (risk ratios between 2.1 and 4.7), both before and after the price reduction.

Conclusions:
Living alone is associated with a substantially increased risk of alcohol-related mortality, irrespective of gender, socioeconomic status, or the specific cause of death. The greater availability of alcohol in Finland after legislation-instituted price reductions in the first three months of 2004 increased in particular the relative excess in fatal liver disease among individuals living alone.

: Please see later in the article for the Editors' Summary


Vyšlo v časopise: Living Alone and Alcohol-Related Mortality: A Population-Based Cohort Study from Finland. PLoS Med 8(9): e32767. doi:10.1371/journal.pmed.1001094
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1001094

Souhrn

Background:
Social isolation and living alone are increasingly common in industrialised countries. However, few studies have investigated the potential public health implications of this trend. We estimated the relative risk of death from alcohol-related causes among individuals living alone and determined whether this risk changed after a large reduction in alcohol prices.

Methods and Findings:
We conducted a population-based natural experimental study of a change in the price of alcohol that occurred because of new laws enacted in Finland in January and March of 2004, utilising national registers. The data are based on an 11% sample of the Finnish population aged 15–79 y supplemented with an oversample of deaths. The oversample covered 80% of all deaths during the periods January 1, 2000–December 31, 2003 (the four years immediately before the price reduction of alcohol), and January 1, 2004–December 31, 2007 (the four years immediately after the price reduction). Alcohol-related mortality was defined using both underlying and contributory causes of death. During the 8-y follow-up about 18,200 persons died due to alcohol-related causes. Among married or cohabiting people the increase in alcohol-related mortality was small or non-existing between the periods 2000–2003 and 2004–2007, whereas for those living alone, this increase was substantial, especially in men and women aged 50–69 y. For liver disease in men, the most common fatal alcohol-related disease, the age-adjusted risk ratio associated with living alone was 3.7 (95% confidence interval 3.3, 4.1) before and 4.9 (95% CI 4.4, 5.4) after the price reduction (p<0.001 for difference in risk ratios). In women, the corresponding risk ratios were 1.7 (95% CI 1.4, 2.1) and 2.4 (95% CI 2.0, 2.9), respectively (p ≤ 0.01). Living alone was also associated with other mortality from alcohol-related diseases (range of risk ratios 2.3 to 8.0) as well as deaths from accidents and violence with alcohol as a contributing cause (risk ratios between 2.1 and 4.7), both before and after the price reduction.

Conclusions:
Living alone is associated with a substantially increased risk of alcohol-related mortality, irrespective of gender, socioeconomic status, or the specific cause of death. The greater availability of alcohol in Finland after legislation-instituted price reductions in the first three months of 2004 increased in particular the relative excess in fatal liver disease among individuals living alone.

: Please see later in the article for the Editors' Summary


Zdroje

1. Holt-LunstadJSmithTBLaytonJB 2010 Social relationships and mortality risk: a meta-analytic review. PLoS Med 7 e1000316 doi:10.1371/journal.pmed.1000316

2. McPhersonMSmith-LovinLBrashearsM 2006 Social isolation in America: changes in core discussion networks over two decades. Am Sociol Rev 71 353 375

3. PutnamRD 2000 Bowling alone: the collapse and revival of American community. New York Simon & Schuster

4. GriffinJ 2010 The lonely society? London Mental Health Foundation Available: http://www.mentalhealth.org.uk/content/assets/PDF/publications/the_lonely_society_report.pdf. Accessed 16 November 2010

5. HuYRGoldmanN 1990 Mortality differentials by marital status: an international comparison. Demography 27 233 250

6. KoskinenSJoutsenniemiKMartelinTMartikainenP 2007 Mortality differences according to living arrangements. Int J Epidemiol 36 1255 1264

7. BurgoaMRedigorERodriquezCGutierrez-FisacJ 1998 Mortality by cause of death and marital status in Spain. Eur J Public Health 8 37 42

8. AkerlindIHörnquistJO 1992 Loneliness and alcohol abuse: a review of evidences of an interplay. Soc Sci Med 34 405 414

9. JoutsenniemiKMartelinTMartikainenPPirkolaSKoskinenS 2006 Living arrangements and mental health in Finland. J Epidemiol Community Health 60 468 475

10. MäkeläPÖsterbergE 2009 Weakening of one more alcohol control pillar: a review of the effects of the alcohol tax cuts in Finland in 2004. Addiction 104 554 563

11. National Research and Development Centre for Welfare and Health 2007 Yearbook of alcohol and drug statistics 2007. Helsinki National Research and Development Centre for Welfare and Health

12. MäkeläP 2000 Alcohol-related mortality during an economic boom and recession. Contemp Drug Probl 26 373 386

13. LahtiRAPenttiläA 2001 The validity of death certificates: routine validation of death certification and its effects on mortality statistics. Forensic Sci Int 115 15 32

14. Statistics Finland 2009 Causes of death 2007. Helsinki Official Statistics of Finland

15. HerttuaKMäkeläPMartikainenP 2007 Differential trends in alcohol-related mortality: a register-based follow-up study in Finland in 1987-2003. Alcohol Alcohol 42 456 464

16. MathersCDFatDMInoueMRaoCLopezAD 2005 Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ 83 171 177

17. Statistics Finland 2007 Causes of death 2006. Helsinki Official Statistics of Finland

18. HaskeyJ 2001 Cohabitation in Great Britain: past, present and future trends—and attitudes. Popul Trends 103 4 25

19. Ben-ShlomoYSmithGDShipleyMMarmotMG 1993 Magnitude and causes of mortality differences between married and unmarried men. J Epidemiol Community Health 47 200 205

20. Ringbäck WeitoftGBurströmBRosénM 2004 Premature mortality among lone fathers and childless men. Soc Sci Med 59 1449 1459

21. KaplanRMKronickRG 2006 Marital status and longevity in the United States population. J Epidemiol Community Health 60 760 765

22. ScafatoEGalluzzoLGandinCGhiriniSBaldereschiM 2008 Marital and cohabitation status as predictors of mortality: a 10-year follow-up of an Italian elderly cohort. Soc Sci Med 67 1456 1464

23. FornariCDonfrancescoCRivaMAPalmieriLPanicoS 2010 Social status and cardiovascular disease: a Mediterranean case. Results from the Italian Progetto CUORE cohort study. BMC Public Health 10 574

24. SchuckitM 2006 Drug and alcohol abuse: a clinical guide to diagnosis and treatment, 6th ed. New York Springer

25. LahtiRAVuoriE 2002 Fatal alcohol poisoning: medico-legal practices and mortality statistics. Forensic Sci Int 126 203 209

26. AwtryEHPhilippidesGJ 2010 Alcoholic and cocaine-associated cardiomyopathies. Prog Cardiovasc Dis 52 289 299

27. Urbano-MarquezAEstruchRNavarro-LopezFGrauJMMontL 1989 The effects of alcoholism on skeletal and cardiac muscle. N Engl J Med 320 409 415

28. MannRESmartRGGovoniR 2003 The epidemiology of alcoholic liver disease. Alcohol Res Health 27 209 219

29. DawsonDA 2001 Alcohol and mortality from external causes. J Stud Alcohol 62 790 797

30. PaljärviTMäkeläPPoikolainenK 2005 Pattern of drinking and fatal injury: a population-based follow-up study of Finnish men. Addiction 100 1851 1859

31. GrahamIAtarDBorch-JohnsenKBoysenGBurellG 2007 European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Atherosclerosis 194 1 45

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PLOS Medicine


2011 Číslo 9
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Autori: MUDr. Tomáš Ürge, PhD.

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