Otrava etanolem a psychotropními látkami u případu s hnilobnými změnami

Je prezentován případ smrtelné otravy paroxetinem, flunitrazepamem a etanolem v terénu hnilobných změn. Kvantitativní toxikologická analýza vykázala, že koncentrace paroxetinu a 7-aminoflunitrazepamu ( metabolitu flunitrazepamu) ve vzorku femorální krve byla 0,28 µg/ml a 0.17 µg/ml. Také byla zjištěna hladina alkoholu 2,90 mg/ml a n-propanolu 0,10 mg/ml. Usuzujeme proto, že smrt nastala v důsledku vzájemné interakce paroxetinu, flunitrazepamu a etanolu. Bylo též uvažováno o vlivu hnilobných změn na forensní toxikologické vyhodnocení.

Klíčová slova:
flunitrazepam – etanol – paroxetine – plynová chromatografie s hmotnostní spektrometrií (GC/MS).

Autoři: Hiroshi Kinoshita ¹; Naoko Tanaka ¹; Mostofa Jamal ¹; Mitsuru Kumihashi ¹; Ayaka Takakura ¹; T. Tobiume ¹; Kunihito Tsutsui ²; Kiyoshi Ameno ¹
Působiště autorů: Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan ¹; Health Sciences, School of Nursing, Faculty of Medicine, Kagawa University, Kagawa, Japan ²
Vyšlo v časopise: Soud Lék., 60, 2015, No. 2, p. 25-27
Kategorie: Původní práce

Souhrn

Klíčová slova:
flunitrazepam – etanol – paroxetine – plynová chromatografie s hmotnostní spektrometrií (GC/MS).

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