New approaches to anticoagulant treatment for senior citizens with atrial fibrillation

Česká verzia

Authors: J. Špác; Bohuslav Kianička
Authors place of work: II. interní klinika LF MU, FN u sv. Anny v Brně
Published in the journal: Kardiol Rev Int Med 2012, 14(1): 22-26

Summary

New approaches to anticoagulant treatment for senior citizens with atrial fibrillation. Anticoagulant treatment for senior citizens with atrial fibrillation represents one of the most frequently administered treatments, with a relatively safe risk profile. Before beginning the procedure, it is necessary to carry out a risk assessment to assist the selection of a suitable therapy and in assessment of the risk of side-effects (bleeding). Until recently, the only anticoagulant was warfarin, which has a number of shortcomings. In recent years, a number of anticoagulant substances have appeared that block the functioning of thrombin or factor X, and which have shown in a number of clinical tests greater effectiveness in the prevention of thromboses connected to lower prevalence of bleeding. New anticoagulants have not only a number of advantages, but also some limitations that must be respected during treatment so that the benefits of new substances are not negated through incorrect use in practice.

Keywords:
anticoagulation treatment – atrial fibrillation – warfarin – gatrans – xabans

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