Long-term left ventricular assist devices in heart failure treatment

Česká verzia

Authors: V. Horváth; P. Němec; J. Ondrášek; H. Bedáňová; P. Fila; P. Pokorný; P. Pavlík; J. Slavík; R. Wagner
Authors place of work: Centrum kardiovaskulární a transplantační chirurgie, Brno
Published in the journal: Kardiol Rev Int Med 2016, 18(4): 253-257

Summary

Heart transplantation remains the gold standard therapy for patients with advanced heart failure. However, long-term left ventricular assist devices (LVAD) became the standard therapy because of the limited number of usable donor grafts and long waiting times. In this paper, we will summarise the history, evolution and function of LVADs. We will also present a review of complications and some specific clinical characteristics of patients with implanted LVAD. Three types of LVADs with continual flow are currently implanted in the Czech Republic: the second-generation LVAD with HeartMate II (Thoratec, USA) axial pump, third-generation LVAD with HeartWare HVAD (Heartware, USA) centrifugal pump, and as a part of clinical trials the newest third generation pump HeartMate III (Thoratec, USA), which is able to generate an artificial pulse. LVADs are already used in Czech Republic as a standard therapy for patients on the waiting list as a bridge to heart transplant. However, in future LVADs will be used for permanent implantation – destination therapy.

Keywords:
mechanical circulatory support – left ventricular assist devices

Zdroje

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