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Measurement and interpretation of cardiac troponins in Europe. Commentary on the studies CAMARGUE and SEKK 2019. Communication for practice.


Authors: B. Friedecký
Authors place of work: Ústav klinické biochemie a diagnostiky, Fakultní nemocnice, Hradec Králové
Published in the journal: Klin. Biochem. Metab., 29, 2021, No. 4, p. 213-215

Summary

International questionnaire on the cardiac troponins, organized by working group of EFLM (CAMARGUE 2019) and national questionnaire performed as part of EQA program of Czech Republic (SEKK 2019) were assessed. Items for assessment are namely frequencies of hs methods, cut-off values, algorithms of sample collection, protocols of results, measurement units, role of POCT, quality control. Results of this assessment were similar for both questionnaires. Guidelines ESC (2012, 2017) served as criteria for assessment. Conclusions from studies help to reaching better step of harmonization and diagnostic effectivity.

Keywords:

Cardiac troponins – hs cTnT/I – cut-off – algorithms of sample collections – postanalytical phase


Zdroje
  1. Collinson, P., Surissaari, J., Akre, K.-M. et al. How well do laboratories adhere to recommended guidelines for cardiac biomarkers management in Europe? The Camargue Marker Guideline Uptake in Europe (CAMARGUE). Study of the European Federation of Laboratory Medicine tsk Group on Cardiac Markers. Clin. Chem., 2021, 57, s. 1144-1152.
  2. Friedecký, B., Kratochvíla, J., Kotaška, K., Štěpánková M., Kardiální markery. Dotazník 2019, FONS 2/2020.   
  3. Steg, P. G., Jame, S. K., Atazi, D. et al., ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur. Heart J., 2012, 33(20), s. 2569–2619.
  4. Ibanez, B., Jones, A., Agewall, S. et al. ESC 2017 guidelines of management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur. Heart J., 2018, 39(2), s. 119-177.
  5. Apple, F. S., Fantz, C. R.., Collinson, P. O. Implementation of high sensitivity and point-of-care cardiac troponin assays into practice:some different thoughts. Clin. Chem., 2021, 67(1), s. 70-78.
  6. Clerico, A., Zanimotto, M., Plebani, M., High-sensitivity assay for cardiac troponins in POCT methods. The future is soon. Clin. Chem. Lab. Med., 2021, 59(9), s. 1477-1478.
Štítky
Clinical biochemistry Nuclear medicine Nutritive therapist
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