Up-to-date management of GBS infection: a case report

Česká verzia

Authors: K. Pinterová; M. Čadová; A. Mocková; M. Matas
Authors place of work: Neonatologické oddělení, FN Plzeň
Published in the journal: Čes-slov Neonat 2022; 28 (2): 131-137.
Category: Case Reports

Summary

Streptococcus agalactiae is a common part of vaginal microflora and its colonization can be either permanent or transient. Czech republic has developed a universal prenatal screening with a vaginal-rectal swab for GBS (group B Streptococcus) between the 35th and 37th week of pregnancy. Women are labeled with GBS status and after assessment of other risk factors, appropriate intrapartum antibiotic prophylaxis (IAP) is implemented.

The presented case report describes the development of early onset GBS sepsis in a late preterm newborn who was born in a secondary-level facility. Since the mother had been GBS negative, the birth took place without the administration of IAP. The newborn developed a fulminant GBS infection and was transferred to a tertiary center in critical condition. Other risk factors of the pregnancy are introduced and the approach of prenatal screening for GBS in different countries is discussed, as well as the strategy of application of IAP and overall changes in the management of neonates at risk of developing early onset GBS disease.

Keywords:

group B Streptococcus – early onset sepsis – prenatal GBS screening – intrapartum antibiotic prophylaxis

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