Primary Heart Tumors as a Cause of Embolization into the Central Nervous System: Ten-Years´ Experience
Authors:
R. Brát; J. Sieja; J. Štětinský
Authors place of work:
Kardiochirurgické centrum FNsP Ostrava
Published in the journal:
Cesk Slov Neurol N 2007; 70/103(3): 278-283
Category:
Short Communication
Summary
The heart tumor is not a frequent cause of embolization into the central nervous system (CNS). The authors have presented their experience with this disorder and focused on patients in whom an embolizing cerebrovascular accident (ECVA) was the first manifestation of a tumor. Patients’ symptomatology, period between appearing the first symptoms up to diagnosing embolism, tumor location, method and outcome of therapy were assessed retrospectively. The results achieved in patients with and those without ECVA were compared. Within 1996–2006, 53 patients with the heart tumor were operated on, out of them 10 (18.9%) experienced ECVA. In ECVA patients, the tumor was located 9× in the left and 1× in the right atrium. In patients without ECVA, the tumor was situated in the left atrium 34×, in the right atrium 7×, in one case it protruded from the mitral valve, and duplicity was seen in two cases. Nine patients (21%) were quite asymptomatic. In patients without ECVA, the period from the first symptoms up to the diagnosis establishing ranged within 3 days – 2 years (mean 101 days). In ECVA sufferers, their interval ranged within 7 days – 16 months (mean 170 days). All the patients underwent a surgery. Perioperative mortality rate in groups with and without ECVA was 0% and 4.5%, respectively. The report has discussed the size of a set, representation of patients with ECVA, tumor location, symptomatology, period from the first symptoms up to the diagnosis establishing, and therapeutical results. The embolization of heart myxomas into the CNS is not a frequent but very severe symptom. Although this symptom should lead to very quick searching for the source of embolization, in practice the period from embolization to establishing the correct diagnosis has been still too long.
Key words:
heart tumor – myxoma – embolization – cerebrovascular accident
Zdroje
1. Castells E, Ferran V, Octavio MC, Calbet JM, Benito M, Fontanillas C et al. Cardiac myxomas: surgical treatment, longterm results and recurence. J Cardiovasc Surg 1993; 34: 49-53.
2. Keeling M, Oberwalder P, Anelli-Monti M. Cardiac myxomas: 24 years of experience in 49 patients. Eur J Cardiothorac Surg 2002; 22: 971–7.
3. MacGowan SW, Sidhu P, Aherne T, Luke D, Wood AE, Neligan MC et al. Atrial myxom: national incidence, diagnosis and surgical management. Ir J Med Sci 1993; 162: 223–6.
4. Gray IR, Williams WG. Recurring cardiac myxoma. Br Heart J 1985; 53: 645–9.
5. Mitgalter E, Lotan H, Schuger L. Cardiac myxomas – surgical experience with a multi-faceted tumor. Thorac Cardiovasc Surg 1987; 35: 115–8.
6. Edwards FH, Hale D, Cohen A, Thompson L, Pezzella AT, Virmani R. Primary cardiac valve tumors. Ann Thorac Surg 1991; 52: 1127–31.
7. Tuna M, Brtko M, Dominik J. Srdeční myxomy. Lék Zpr LF UK Hradec Králové 2004; 49: 51–7.
8. Sutton GC, Chaterjee K. Srdeční nádory. Kardiologická revue 2004; 1: 39–46.
9. Reynen K. Cardiac myxomas. N Engl J Med 1995; 333: 1610–17.
10. Pinede L, Duhaut P, Loire R. Clinical presentation of left atrial cardiac myxoma: a series of 112 consecutive cases. Medicine 2001; 80: 159–72.
11. Butany J, Nair V, Naseemuddin A, Nair GM, Catton C, Yau T. Cardiac tumours: diagnosis and management. The Lancet Oncology 2005; 6: 219–28.
12. Křížová B, Frídl P, Podzimková M. Recidiva myxomu v levé komoře srdeční. Cor Vasa 2004; 46: 389–91.
13. Ekinci EI, Donnan GA. Neurological manifestations of cardiac myxoma: a review of the literature and report of cases. Intern Med J 2004; 34: 243–9.
14. Jones DR, Warden HE, Murray GF. Cardiac myxomas: a 30 year clinical experience. Ann Thorac Surg 1995; 59: 851–6.
Štítky
Paediatric neurology Neurosurgery NeurologyČlánok vyšiel v časopise
Czech and Slovak Neurology and Neurosurgery
2007 Číslo 3
- Memantine Eases Daily Life for Patients and Caregivers
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Metamizole vs. Tramadol in Postoperative Analgesia
Najčítanejšie v tomto čísle
- Chiari Malformation: Own Experience
- Osmotic Demyelination Syndrome – MRI Diagnosis: a Case Report
- The Brain MR Imaging in Patients with Myotonic Dystrophy DM 1
- Osteoplastic Decompressive Craniotomy