Motor Aspects of Speech Imparment in Parkinson‘s Disease and their Assessment

Česká verzia

Authors: J. Mekyska ¹; Z. Smékal ¹; M. Košťálová ^3,4; M. Mračková ^2,3; S. Skutilová ⁴; I. Rektorová ^2,3
Authors place of work: SPLab, Ústav telekomunikací, FEKT VUT v Brně ¹; I. neurologická klinika LF MU a FN u sv. Anny v Brně ²; CEITEC MU, Brno ³; Neurologická klinika LF MU a FN Brno ⁴
Published in the journal: Cesk Slov Neurol N 2011; 74/107(6): 662-668
Category: Review Article

Summary

Patients with Parkinson’s disease (PD) often suffer from hypokinetic dysarthria (HD) involving impairment of phonation, articulation, prosody and speech fluency. Our paper focuses on parameters used to evaluate motor aspects of speech and on methods of relevant data collection and analysis. An overview of specific parameters of HD and methods used for its evaluation may facilitate development of a diagnostic system for HD and of suitable measures for the assessment of its progression.

Key words:
Parkinson’s disease – hypokinetic dysarthria – speech parameters

Zdroje

1. Parkinson J. An essay on the shaking palsy. J Neuropsychiatry Clin Neurosci 2002; 14(2): 223–236.

2. Hornykiewicz O. Biochemical aspects of Parkinson‘s disease. Neurology 1998; 51 (Suppl 2): S2–S9.

3. Brodal P. The Central Nervous System: Structure and Function. 3rd ed. New York: Oxford University Press 2003.

4. Kent RD, Kent JF, Duffy J, Weismer G. The dysarthrias: speech-voice profiles, related dysfunctions, and neuropathology. J Med Speech Lang Pathol 1998; 6(4): 165–211.

5. Lang AE, Lozano AM. Parkinson‘s disease. First of two parts. N Engl J Med 1998; 339(15): 1044–1053.

6. Hoehn MM, Yahr MD. Parkinsonism: onset, progression, and mortality. Neurology 1967; 17 (Suppl 3): 427–442.

7. Goberman AM, Coelho C. Acoustic analysis of parkinsonian speech I: speech characteristics and L-Dopa therapy. NeuroRehabilitation 2002; 17(3): 237–246.

8. Jankovic J, Kapadia AS. Functional decline in Parkinson disease. Arch Neurol 2001; 58(10): 1611–1615.

9. Hilker R, Schweitzer K, Coburger S, Ghaemi M, Weisenbach S, Jacobs A et al. Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluorodopa F 18 activity. Arch Neurol 2005; 62(3): 378–382.

10. Rektorová I. Současné možnosti diagnostiky a terapie Parkinsonovy nemoci. Neurol. prax 2009; 10 (Suppl 2): 5–36.

11. Hartelius L, Svensson P. Speech and swallowing symptoms associated with Parkinson‘s disease and multiple sclerosis: a survey. Folia Phoniatr Logop 1994; 46(1): 9–17.

12. Hammen VL, Yorkston KM. Speech and pause characteristics following speech rate reduction in hypokinetic dysarthria. J Commun Disord 1996; 29(6): 429–445.

13. Goberman AM, McMillan J. Relative speech timing in Parkinson’s disease. Commun Science Disord 2005; 32: 22–29.

14. Sapir S, Ramig L, Fox C. Speech, swallowing disorders in Parkinson disease. Curr Opin Otolaryngol Head Neck Surg 2008; 16(3): 205–210.

15. Spencer KA, Rogers MA. Speech motor programming in hypokinetic and ataxic dysarthria. Brain Lang 2005; 94(3): 347–366.

16. Goberman AM. Correlation between acoustic speech characteristics and non-speech motor performance in Parkinson disease. Med Sci Monit 2005; 11(3): 109–116.

17. Shao J, Maccallum JK, Zhang Y, Sprecher A, Jiang JJ. Acoustic analysis of the tremulous voice: assessing the utility of the correlation dimension and perturbation parameters. J Commun Disord 2010; 43(1): 35–44.

18. Canter GJ. Speech characteristics of patients with Parkinson‘s disease: I. intensity, pitch, and duration.J Speech Hear Disord 1963; 28(3): 221–29.

19. Holmes RJ, Oates JM, Phyland DJ, Hughes AJ. Voice characteristics in the progression of Parkinson‘s disease. Int J Lang Commun Disord 2000; 35(3): 407–418.

20. Metter EJ, Hanson WR. Clinical and acoustical variability in hypokinetic dysarthria. J Commun Disord 1986; 19(5): 347–366.

21. Doyle P, Raade A, Pierre AS, Desai S. Fundamental frequency and acoustic variability associated with production of sustained vowels by speakers with hypokinetic dysarthria. J Med Speech Lang Pathol 1995; 3: 41–50.

22. Zwirner P, Barnes GJ. Vocal tract steadiness: a measure of phonatory and upper airway motor control during phonation in dysarthria. J Speech Hear Res 1992; 35(4): 761–768.

23. Rusz J, Cmejla R, Ruzickova H, Ruzicka E. Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson‘s disease. J Acoust Soc Am 2011; 129(1): 350–367.

24. Hertrich I, Ackermann H. Gender-specific vocal dysfunctions in Parkinson‘s disease: electroglottographic and acoustic analyses. Ann Otol Rhinol Laryngol 1995; 104(3): 197–202.

25. Jiménez-Jiménez FJ, Gamboa J, Nieto A, Guerrero J, Orti-Pareja M, Molina JA et al. Acoustic voice analysis in untreated patients with Parkinson‘s disease. Parkinsonism Relat Disord 1997; 3(2): 111–116.

26. Kent R, Kim H, Weismer G, Kent J, Rosenbek J, Brooks B et al. Laryngeal dysfunction in neurological disease: amyotrophic lateral sclerosis, Parkinson disease, and stroke. J Med Speech Lang Pathol 1994; 2: 157–175.

27. Baker KK, Ramig LO, Luschei ES, Smith ME. Thyroarytenoid muscle activity associated with hypophonia in Parkinson disease and aging. Neurology 1998; 51(6): 1592–1598.

28. Colton RH, Casper JK, Leonard R. Understanding voice problems: a physiological perspective for diagnosis and treatment. 3rd ed. Philadelphia: Lippincott Williams & Wilkins 2005.

29. Roy N, Nissen SL, Dromey C, Sapir S. Articulatory changes in muscle tension dysphonia: evidence of vowel space expansion following manual circumlaryngeal therapy. J Commun Disord 2009; 42(2): 124–135.

30. Countryman S, Ramig L. Effects of intensive voice therapy on voice deficits associated with bilateral thalamotomy in Parkinson disease: a case study. J Med Speech Lang Pathol 1993; 1(4): 233–250.

31. Ramig LO, Sapir S, Fox C, Countryman S. Changes in vocal loudness following intensive voice treatment (LSVT) in individuals with Parkinson‘s disease: a comparison with untreated patients and normal age-matched controls. Mov Disord 2001; 16(1): 79–83.

32. Solomon NP, Hixon TJ. Speech breathing in Parkinson‘s disease. J Speech Hear Res 1993; 36(2): 294–310.

33. De Letter M, Santens P, De Bodt M, Van Maele G, Van Borsel J, Boon P. The effect of levodopa on respiration and word intelligibility in people with advanced Parkinson‘s disease. Clin Neurol Neurosurg 2007; 109(6): 495–500.

34. Adler CH, Ahlskog JE. Parkinson‘s disease and movement disorders: diagnosis and treatment guidelines for the practicing physician. 1st ed. Totowa (NJ): Humana Press 2000.

35. Logemann JA, Fisher HB, Boshes B, Blonsky ER. Frequency and cooccurrence of vocal tract dysfunctions in the speech of a large sample of Parkinson patients. J Speech Hear Disord 1978; 43(1): 47–57.

36. McNeil MR, Rosenbeck JC, Aronson AE. The dysarthrias: physiology, acoustics, perception, management. San Diego: College Hill Press 1984.

37. Logemann JA, Fisher HB. Vocal tract control in Parkinson‘s disease: phonetic feature analysis of misarticulations. J Speech Hear Disord 1981; 46(4): 348–352.

38. Canter GJ. Speech characteristics of patients with Parkinson‘s disease: III. articulation, diadochokinesis, and over-all speech adequacy. J Speech Hear Disord 1965; 30(3): 217–224.

39. Ackermann H, Konczak J, Hertrich I. The temporal control of repetitive articulatory movements in Parkinson‘s disease. Brain Lang 1997; 56(2): 312–319.

40. Rosen KM, Kent RD, Delaney AL, Duffy JR. Parametric quantitative acoustic analysis of conversation produced by speakers with dysarthria and healthy speakers. J Speech Lang Hear Res 2006; 49(2): 395–411.

41. Tjaden K, Watling E. Characteristics of diadochokinesis in multiple sclerosis and Parkinson‘s disease. Folia Phoniatr Logop 2003; 55(5): 241–259.

42. Fletcher SG. Time-by-count measurement of diadochokinetic syllable rate. J Speech Hear Res 1972; 15(4): 763–770.

43. Sapir S, Ramig LO, Spielman JL, Fox C. Formant centralization ratio (FCR): a proposal for a new acoustic measure of dysarthric speech. J Speech Lang Hear Res 2010; 53(1): 1–20.

44. Skodda S, Rinsche H, Schlegel U. Progression of dysprosody in Parkinson’s disease over time – a longitudinal study. Mov Disord 2009; 24(5): 716–722.

45. Viallet F, Teston B, Ludovic J. Effects of pharmacological versus electrophysiological treatments in Parkinsonian dysprosodie. Curr Opin Otolaryngol Head Neck Surg 2008; 13(3): 205–210.

46. Caekebeke JF, Jennekens-Schinkel A, van der Linden ME, Buruma OJ, Roos RA. The interpretation of dysprosody in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry 1991; 54(2): 145–148.

47. Moretti R, Torre P, Antonello RM, Capus L, Gioulis M, Zambito Marsala S et al. Speech initiation hesitation following subthalamic nucleus stimulation in a patient with Parkinson’s disease. Eur Neurol 2003; 49(4): 251–253.

48. Stracciari A, Guarino M, Cirignotta F, Pazzaglia P. Development of palilalia after stereotaxic thalamotomy in Parkinson’s disease. Eur Neurol 1993; 33(3): 275–276.

49. Cantiniaux S, Vaugoyeau M, Robert D, Horrelou--Pitek C, Mancini J, Witjas T et al. Comparative analysis of gait and speech in Parkinson‘s disease: hypokinetic or dysrhythmic disorders? J Neurol Neurosurg Psychiatry 2010; 81(2): 177–184.

50. Gentil M, Pollak P, Perret J. Parkinsonian dysarthria. Rev Neurol 1995; 151(2): 105–112.

51. Fischer E, Goberman AM. Voice onset time in Parkinson disease. J Commun Disord 2010; 43(1): 21–34.

52. Goberman AM, Coelho C, Robb M. Phonatory characteristics of parkinsonian speech before and after morning medication: the ON and OFF states. J Commun Disord 2002; 35(3): 217–239.

53. Skodda S, Visser W, Schlegel U. Short- and long-term dopaminergic effects on dysarthria in early Parkinson’s disease. J Neural Transm 2010; 117(2): 197–205.

54. Le Dorze G, Ryalls J, Brassard C, Boulanger N, Ratte D. A comparison of the prosodic characteristics of the speech of people with Parkinson’s disease and Friedreich’s ataxia with neurologically normal speakers. Folia Phoniatr Logop 1998; 50(1): 1–9.

55. Rektorova I, Barrett J, Mikl M, Rektor I, Paus T. Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson‘s disease. Mov Disord 2007; 22(14): 2043–2051.

56. Duffy JR, Clinic M. Motor speech disorders: substrates, differential diagnosis, and management. 2nd ed. St. Louis: Mosby 2005.

57. Harel B, Cannizzaro M, Snyder PJ. Variability in fundamental frequency during speech in prodromal and incipient Parkinson’s disease: a longitudinal case study. Brain Cogn 2004; 56(1): 24–29.

58. Kegl J, Cohen H, Poizner H. Articulatory consequences of Parkinson’s disease: perspectives from two modalities. Brain Cogn 1999; 40(2): 355–386.

59. Flint AJ, Black SE, Campbell-Taylor I, Gailey GF, Levinton C. Acoustic analysis in the differentiation between Parkinson’s disease and major depression. J Psycholinguist Res 1992; 21(5): 383–399.

60. Ho AK, Iansek R, Bradshaw JL. Regulation of parkinsonian speech volume: the effect of interlocuter distance. J Neurol Neurosurg Psychiatry 1999; 67(2): 199–202.

61. Ho AK, Bradshaw JL, Iansek R, Alfredson R. Speech volume regulation in Parkinson’s disease: effects of implicit cues and explicit instructions. Neuropsychologia 1999; 37(13): 1453–1460.

62. Sanabria J, Ruiz PG, Gutierrez R, Marquez F, Escobar P, Gentil M et al. The effect of levodopa on vocal function in Parkinson’s disease. Clin Neuropharmacol 2001; 24(2): 99–102.

63. Ho AK, Iansek R, Bradshaw JL. Motor instability in Parkinsonian speech intensity. Neuropsychiatry Neuropsychol Behav Neurol 2001; 14(2): 109–116.

64. Teager H. Some observations on oral air flow during phonation. Acoustics, Speech, Signal Processing, IEEE Transactions on 1980; 28(5): 599–601.

65. Kaiser JF. On a simple algorithm to calculate the “energy” of a signal. International Conference on Acoustics, Speech, and Signal Processing; 1990 Apr 3–6; Albuquerque, New Mexico: 381–384.

66. Hirose H. Pathophysiology of motor speech disorders (dysarthria). Folia Phoniatr (Basel) 1986; 38(2–4): 61–88.

67. Ludlow CL, Connor NP, Bassich CJ. Speech timing in Parkinson’s and Huntington’s disease. Brain Lang 1987; 32(2): 195–214.

68. Goberman AM, Coelho CA, Robb MP. Prosodic characteristics of parkinsonian speech: the effect of levodopa-based medication. J Med Speech Lang Pathol 2005; 13(1): 51–68.

69. Goberman AM, Elmer LW. Acoustic analysis of clear versus conversational speech in individuals with Parkinson disease. J Commun Disord 2005; 38(3): 215–230.

70. Weismer G, Jeng JY, Laures JS, Kent RD, Kent JF. Acoustic and intelligibility characteristics of sentence production in neurogenic speech disorders. Folia Phoniatr Logop 2001; 53(1): 1–18.

71. Hillenbrand J, Getty LA, Clark MJ, Wheeler K. Acoustic characteristics of American English vowels. J Acoust Soc Am 1995; 97(5): 3099–3111.

72. Sapir S, Spielman JL, Ramig LO, Story BH, Fox C. Effects of intensive voice treatment (the Lee Silverman voice treatment [LSVT]) on vowel articulation in dysarthric individuals with idiopathic Parkinson disease: acoustic and perceptual findings. J Speech Lang Hear Res 2007; 50(4): 899–912.

73. Kent RD, Kim YJ. Toward an acoustic typology of motor speech disorders. Clin Linguist Phon 2003; 17(6): 427–445.

74. Liu H, Tsao F, Kuhl PK. The effect of reduced vowel working space on speech intelligibility in Mandarin-speaking young adults with cerebral palsy. J Acoust Soc Am 2005; 117(6): 3879–3889.

75. Lisker L, Abramson A. A cross-language study of voicing in initial stops: acoustical measurements. Word 1964; 20(3): 384–422.

76. Kent RD. Acoustic analysis of speech. 2nd ed. San Diego: Singular 2001.

77. Weismer G. Articulatory characteristics of parkinsonian dysarthria: segmental and phrase-level timing, spirantization, and glottal-supraglottal coordination. San Diego: College-Hill 1984.

78. Forrest K, Weismer G, Turner G. Kinematic, acoustic and perceptual analyses of connected speech produced by parkinsonian and normal geriatric males. J Acoust Soc Am 1989; 85(8): 2608–2622.

79. Ozsancak C, Auzou P, Jan M, Leonardo MG, Hannequin D. Pseudobulbar and parkinsonian dysarthria: an acoustical analysis. J Neurol 1997; 244: 244–253.

80. Bunton K, Weismer G. Segmental level analysis of laryngeal function in persons with motor speech disorders. Folia Phoniatr Logop 2002; 54(5): 223–239.

81. Miller JL, Green KP, Reeves A. Speaking rate and segments: a look at the relation between speech production and speech perception for the voicing contrast. Phonetica 1986; 43: 106–115.

82. Summerfield Q. Articulatory rate, perceptual constancy in phonetic perception. J Exp Psychol Hum Percept Perform 1981; 7(5): 1074–1095.

83. Berry W. Clinical Dysarthria. San Diego: College-Hill 1983.

84. Goberman AM, Blomgren M. Fundamental frequency change during offset and onset of voicing in individuals with Parkinson disease. J Voice 2008; 22(2): 178–191.