Multiple Sclerosis, Infertility and its Treatment

Česká verzia

Authors: I. Šrotová ^1,2; I. Crha ³ ; E. Vlčková ^1,2; M. Svobodová ^1,2; E. Nekvapilová ²; P. Štourač ^1,2; J. Bednařík ^1,2
Authors place of work: Neurologická klinika LF MU a FN Brno ¹; CEITEC – Středoevropský technologický institut, MU, Brno ²; Gynekologicko-porodnická klinika LF MU a FN Brno ³
Published in the journal: Cesk Slov Neurol N 2015; 78/111(6): 655-660
Category: Review Article

Summary

Multiple sclerosis is a common autoimmune disease affecting young people, with onset usually at the age of 20– 40 years. During these decades patients are usually planning pregnancy. In patients with multiple sclerosis fertility seems to be slightly impaired. Several factors might contribute to this condition. It is mainly sexual dysfunctions, which belong to comparatively common symptoms of the disease, hormonal alteration, concomitant (autoimmune) disease and specific therapy of multiple sclerosis. Psychosocial factors have an influence on fertility and its therapy. The aim of this review is description of factors potentially interfering with fertility in multiple, the current applications of assisted reproductive techniques and its influence on course of multiple sclerosis.

Key words:
multiple sclerosis – infertility – in vitro fertilisation – endometriosis – sexual dysfunctions – sexual hormons

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

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