Development of cognitive performance in children before and after surgical treatment of pharmacoresistant temporal lobe epilepsy

Česká verzia

Authors: K. Bukačová- ^{1 3}; A. Maulisová ^2,3; A. Jahodová ²; M. Kudr ²; G. A. Ramos Rivera ⁴; P. Kršek ²
Published in the journal: Cesk Slov Neurol N 2024; 87(4): 275-281
Category: Short Communication
doi: https://doi.org/10.48095/cccsnn2024275

Summary

This case study focuses on the long-term cognitive sequelae of temporal lobe epilepsy (TLE) in childhood and their influence by surgical treatment. The study follows four pediatric patients with TLE who underwent successful resectional epilepsy surgery at the Motol Epilepsy Center. While the standard measure of success of epilepsy surgery is postoperative seizure cessation, reduced medication, and improved quality of life, our study also underscores the importance of monitoring the overall neuropsychological profile and providing additional clinical-psychological care. Monitoring of intelligence performance alone is insufficient to fully understand cognitive development after epilepsy surgery. In the cases reported, we documented a gradual consolidation of cognitive functions over time. Comprehensive care, interdisciplinary collaboration, and early indication for epilepsy surgery are crucial to achieve an overall favorable outcome. Early referral of pharmacoresistant patients to specialized centers and prompt effective treatment of epileptic seizures are essential to prevent long-term negative consequences of untreated epilepsy, including cognitive difficulties and psychosocial problems. Simultaneously, further research into the neuropsychology of TLE in children and the development of more effective treatment and support strategies for these patients and their families are essential.

Keywords:

epilepsy surgery – Intelligence – temporal lobe epilepsy – longitudinal perspective – cognition in children – cognitive development

Zdroje

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