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Indication Avastin in Ophthalmology


Authors: J. Studnička
Authors place of work: Oční klinika FN a LF UK, Hradec Králové, přednosta prof. MUDr. Pavel Rozsíval, CSc., FEBO
Published in the journal: Čes. a slov. Oftal., 66, 2010, No. 5, p. 229-233
Category: Original Article

Summary

Bevacizumab (Avastin) is a humanized monoclonal antibody to vascular endothelial growth factor A that is approved for the treatment of metastatic colorectal cancer. Although this drug is off-label for intraocular use, it has been widely used as intravitreal therapy for lot of ocular diseases. This paper will describe the efficacy and safety of the intraocular Avastin in the treatment of ocular diseases. The results described in the article warrant further study of bevacizumab in larger, controlled, randomized trials.

Key words:
Avastin, vascular endothelial growth factor A, bevacizumab


Zdroje

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Štítky
Ophthalmology
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