On teaching the chemistry of pharmaceutical auxiliary substances within the framework of pharmaceutical education in the Czech and Slovak Republics
Authors:
Jan Šubert
Published in the journal:
Čes. slov. Farm., 2011; 60, 4-6
Category:
Review Articles
Summary
The paper emphasizes the need of the introduction of the subject Chemistry of Pharmaceutical Auxiliaries into the Pharmacy study programme at more colleges in the Czech and Slovak Republics. It also introduces and discusses some topics for possible extension of the content of the courses of the subject (the presented examples are taken form the field of analytical chemistry of pharmaceutical auxiliaries).
Key words:
chemistry of pharmaceutical auxiliaries – education
Zdroje
1. Melichar, B., Čeladník, M., Hartl, J., Chocholoušová, J., Kňažko, L., Nováček, L., Palát, K., Sova, J., Vanžura, J.: Chemická léčiva. 3. vyd. Praha: Avicenum 1987; 985 s.
2. Beneš, L.: Osobní sdělení, 2001.
3. Farmaceutická fakulta v Hradci Králové: Sylabus předmětu Farmaceutická chemie. http://www.faf.cuni.cz/ studium/magisterske/farmacie/sylaby/kfchkl/Stranky/sylab_farm_farmaceuticka_chemie.aspx (27. 11. 2010).
4. Univerzita veterinárného lekárstva a farmácie v Košiciach: Informačný list predmetu Farmaceutická chémia, Sylabus predmetu (dátum poslednej úpravy 28. 9. 2010).
5. Farmaceutická fakulta UK v Bratislave: Farmaceutická chémia – Stručná osnova predmetu. http://www.fpharm. uniba.sk/index.php?id=2544 (8. 12. 2010).
6. Šubert, J.: Návrh nového povinně-volitelného předmětu Chemie farmaceutických pomocných látek. Zasláno vedení Farmaceutické fakulty VFU Brno dne 27. 4. 2006.
7. Farsa, O.: Pharmaceutical excipients from the point of view of a medicinal chemist. Khimija 2009; 18, 165–171. http://khimiya.org/pdfs/EKHIMIYA_18_5_FARSA_L.pdf (27. 11. 2010).
8. Šubert, J., Čižmárik, J.: Application of instrumental colour measurement in development and quality control of drugs and pharmaceutical excipients. Pharmazie 2008; 63, 331–336.
9. Wou, L-S., Mulley, B. A.: Effect of dispersion on the coloring properties of aluminum dye lakes. J. Pharm. Sci. 1988; 77, 866–871.
10. Soriano, M., Melgosa, M., Sánchez-Maranón, M., Delgado, G., Gámiz, E., Delgado, R.: Whiteness of talcum powders as a quality index for pharmaceutical uses. Color Res. Appl. 1998; 23, 178–185.
11. Šubert, J., Farsa, O., Cieslarová, M.: Efficiency of stabilization of low level of coloration of Castellani’s paint without fuchsine with disodium edetate. Pharmazie 2006; 61, 1049–1050.
12. Schulz, R., Gerhards, R.: Optimization of the potentiometric titration of ionic detergents. International Laboratory 1994; 24, 10–14.
13. Schulz, R.: Titrimetric determination of surfactants and pharmaceuticals. Herrisau: Metrohm 1999; 242 s.
14. Thoma, K., Ullmann, E., Loos, P.: Zur Gehaltbestimmung grenzflächenaktiver quartärer Ammoniumverbindungen (Invertseifen) mit Hilfe Flockungsreaktion. Arch. Pharm. 1963; 296, 417–420.
15. Mizuguchi, H., Yasuda, H., Kaneko, E., Yotsuyanagi, T.: Drop based visual fluorometry of aluminium at ppb level with 2,2’-dihydroxyazobenzene by using octadecylsilanized silica thin layer. Chem. Lett. 1997; 895–896.
16. Mizuguchi, H., Kaneko, E., Yotsuyanagi, T.: Visual fluorimetry of trace aluminium by specific immobilization with o,o’-dihydroxyazobenzene on an octadecylsilanized silica thin layer. Analyst 2000; 125, 1667–1671.
17. Český lékopis 2009, 1.–3. díl. Praha: Grada Publishing 2009; 3942 s.
18. Adeloju, S. B., Bond, A. M.: Influence of laboratory environment on the precision and accuracy of trace element analysis. Anal. Chem. 1985; 57, 1728–1733.
19. Caraballo, I., Rabasco, A. M., Fernández-Arévalo, M.: Study of thiomerosal degradation mechanism. Int. J. Pharm. 1993; 89, 213–221.
20. Tan, M., Parkin, J. E.: Route of decomposition of thiomersal (thiomerosal). Int. J. Pharm. 2000; 208, 23–34.
21. Šubert, J., Farsa, O., Marečková, M.: Stability evaluation of methylparaben and propylparaben in their solution Aqua conservans using HPLC. Sci. Pharm. 2007; 75, 171–177.
22. Thompson, M. J., Fell, A. F., Clark, B. J., Robinson, M. R.: LC studies on the potential interaction of paraben preservatives with sorbitol and glycerol. J. Pharm. Biomed. Anal. 1993; 11, 233–240.
23. Hensel, A., Leisenheimer, S., Müller, A., Wolf-Heuss, E., Engel, J., Busker, E.: Transesterification reactions of parabens (alkyl 4-hydroxybenzoates) with polyols in aqueous solution. J. Pharm. Sci. 1995; 84, 115–118.
24. Ma, M., DiLollo, A., Mercuri, R., Lee, T., Bundang, M., Kwong, E.: HPLC and LC-MS studies of the transesterification reaction of methylparaben with twelve 3- to 6-carbon sugar alcohols and propylene glycol and the isomerization of the reaction products by acyl migration. J. Chromatogr. Sci. 2002; 40, 170–177.
25. Blanco, M., Coello, J., Iturriaga, H., Maspoch, S., Romero, M. A.: Resolution of isomers of sorbitolparaben esters by chromatographic and electrophoretic techniques. J. Chromatogr. B 2001; 752, 99–105.
26. Kalász, H., Antal, I.: Drug excipients. Current Medicinal Chemistry, 2006; 13, 2535–2563.
27. Souhrn údajů o přípravku Differine krém. http://www. leky.sukl.cz/modules/medication/detail.php?code=0046643&tab=texts (6. 12. 2010).
28. Souhrn údajů o přípravku Excipial U Lipolotio. http://www.leky.sukl.cz/modules/medication/detail.php?code=0016462&tab=texts (6. 12. 2010).
29. Souhrn údajů o přípravku Micetal gel. http://www.leky. sukl.cz/modules/medication/detail.php?code=0053904&tab=texts (6. 12. 2010).
Štítky
Pharmacy Clinical pharmacologyČlánok vyšiel v časopise
Czech and Slovak Pharmacy
2011 Číslo 1
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