Corelation between hyperviscosity of the ejaculate and physical-morphological and biochemical parameters

Česká verzia

Authors: L. Bobák ¹; J. Rosocha ¹; L. Lehocká ¹; A. Halagovec ²; M. Hrivňák ³; V. Kraus ⁴; J. Petrovičová ⁵
Authors place of work: Združená tkanivová banka, Lekárska fakulta Univerzity P. J. Šafárika a FN L. Pasteura, Košice, prednosta MVDr. J. Rosocha, CSc. ¹; Klinika dermatovenerológie, LF Univerzity P. J. Šafárika a FN L. Pasteura, Košice, prednostka doc. MUDr. J. Jautová, PhD., mim. prof. ²; Oddelenie urológie, Nemocnica Šaca, a. s. ³; 1. gynekologicko-pôrodnicka klinika, LF Univerzity P. J. Šafárika a FN L. Pasteura, Košice, prednosta doc. MUDr. V. Kraus, CSc. ⁴; Ústav lekárskej informatiky, Lekárska fakulta Univerzity P. J. Šafárika, Košice, prednosta Ing. J. Majerník, PhD. ⁵
Published in the journal: Ceska Gynekol 2009; 74(3): 219-224

Summary

Objective:
The aim of our study was to investigate the corelation between hyperviscosity and physical-morphological and biochemical parameters of the ejaculate and potential influence of local infections on spermatic plasma viscosity and observed parameters.

Design:
Retrospective analysis.

Setting:
Associated Tissue Bank of P. J. Šafárik University of Faculty of Medicine and L. Pasteur Faculty Hospital, Košice, Slovak Republic.

Methods:
The study was based on semen samples showing increased viscosity obtained from 100 consecutive men undergoing fertility assessment (median 35 years, range 27–49 years) in Associated Tissue Bank between years 1996 and 2006. The ejaculates were obtained by masturbation after 2–7 days of sexual abstinence (median 5 days).

Results:
Increased viscosity correlated with lower motility and increased pathology (95% and 91%, respectively). Within the diagnosis of asthenozoospermia there was a correlation between PMN (polymorphonuclear granulocytes) (95%), higher seminal fluid pH (94%), decreased sperm vitality (100%), decreased total seminal plasma fructose (100%) and positive microbiology (95%).

There was significant positive correlation between high visco-elasticity and positive microbiology (85%), although a leukocytospermia (>1 x 106/mL) was present just in 10% of the semen samples.

Conclusion:
Hyper-visco-elasticity is simple but important parameter of men fertility assessment and is associated with the diagnosis of asthenoteratozoospermia. It is suggested from our patient data that decrease of the leukocytospermia cutoff criteria could detect a chronic and/or latent infection of the urogenital tract. Furthermore, combination of the diagnoses of viscopathy and asthenoteratozoospermia seems as potential marker and indication, respectively, for microbiology examination.

Key words:
hyperviscosity of ejaculate, asthenoteratozoospermia, urogenital infections.

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