Female sexual desire disorders – prevalence, classification and treatment possibilities

Česká verzia

Authors: Z. Pastor
Authors place of work: NZZ GONA, Soukromé sexuologické centrum, Praha, vedoucí lékař MUDr. Z. Pastor
Published in the journal: Ceska Gynekol 2011; 76(1): 59-64

Summary

Objective:
Description of female Hypoactive Sexual Desire Disorder (HSDD) and its prevalence, information on possible ways of diagnosis, definition of models of female sexual behaviour, classification of female sexual dysfunctions and perspective on treatment possibilities.

Subject:
Systematic review.

Setting:
GONA, Private Sexuology Centre, Prague.

Subject and Methods:
Current literature review.

Conclusion:
Low sexual desire is present in more than 40% of the female population.

10-16% of women report personal distress associated with low sexual desire and which is characteristic of HSDD. Standardized questionnaires are used for HSDD diagnosis. Current treatment modalities do not provide satisfactory results and require further research.

Key words:
low sexual desire, hypoactive sexual desire disorder (HSDD), female sexual dysfunctions (FSD).

Zdroje

1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Text revision. Washington, DC: American Psychiatric Press, 2000.

2. Basson, R., Berman, J., Burnett, A., et al. Report of the International Consensus Development Conference on Female Sexual Dysfunction: definitions and classifications. J Urol, 2000, 163, 3, p. 888-893.

3. Basson, R., Althof, S., Davis, S., et al. Summary of the recommendations on sexual dysfunctions in women. J Sex Med, 2004, 1, p. 24-34.

4. Basson, R., Wierman, ME., van Lankveld, J., et al. Summary of recommendations on sexual dysfunctions in women. J Sex Med, 2010, 7, p. 314-326.

5. Brock, G., Nicolosi, A., Glasser, DB., et al. Sexual problems in mature men and women: Results of global study. Int J Import Res, 2002, 14, 3 (suppl), p. 57-58.

6. Burri, AV., Lynn, MC., Spector, TD. The genetics and epidemiology of Female Sexual Dysfunction: a review. J Sex Med, 2009, 6, p. 646-657.

7. Clayton, AH. Sexual function and dysfunction in women. Psychiatr Clin North Am, 2003, 26, p. 673-682.

8. Clayton, AH., Montejo, AL. Major depressive disorder, antidepressants and sexual dysfunction. J Clin Psychiatry, 2006, 67, 6 (suppl), p. 33-37.

9. Clayton, AH., Goldfischer, ER., Goldstein, I., et al. Validation of the Decreased Sexual Desire Screener (DSDS): a brief diagnostic instrument for generalized acquired female Hypoactive Sexual Desire Disorder (HSDD). J Sex Med, 2009, 6, p. 730-738.

10. Dennerstein, L., et al. Attitudes toward and frequency of partner interactions among women reporting decreased sexual desire. J Sex Med 2009, 6, p. 1668-1673.

11. DeRogatis, LR.,Rosen, R., Leiblum, S., et al. The Female Sexual Distress Scale (FSDS): initial validation of a standardized scale for assessment of sexually related personal distress in women. J Sex Marital Ther, 2002, 28, p. 317-330.

12. DeRogatis, L., Clayton, A., Lewis-D’Agostino, D., et al. Validation of the female sexual distress scale - revised for assessing distress in women with Hypoactive Sexual Desire Disorder. J Sex Med, 2008, 5, p. 357-364.

13. Female Sexual Function Index (FSFI) [online]. last revision 25.2. 2000 [cit. 2009-08-03]. Dostupný na WWW: < http://www.fsfi-questionnaire.com>.

14. Frank, JE., Mistretta, P., Will, J. Diagnosis and treatment of female sexual dysfunction. Am Fam Physician, 2008, 77, p. 635-642.

15. Goldstein, I., Meston, MS., Davis, SR., et al. Women’s sexual function and dysfunction. London: Taylor and Francis, 2006.

16. Graziottin, A. Prevalence and evaluation of sexual health problems – HSDD in Europe. J Sex Med, 2007, 4, 3 (suppl), p. 211-219.

17. Hayes, RD., Dennerstein, L., Bennett, CM., et al. What is the “true” prevalence of female sexual dysfunctions and does the way we assess these conditions have an impact? J Sex Med, 2008, 5, p. 777-787.

18. Hubayter, Z., Simon, JA. Testosterone therapy for sexual dysfunction in postmenopausal women. Climacteric, 2008, 11, p. 181-191.

19. Janssen, E., Bancroft, J. The dual control model. The role of sexual inhibition and excitation in sexual arousal and behavior. In Janssen, E. The psychophysiology of sex. Bloomington: Indiana University Press, 2007, p. 197-222.

20. Kaplan, HS. Disorders of sexual desire. New York: Brunner/Mazel Publishers Inc, 1979.

21. Krychman, ML., Stelling, CJ., Carter, J., et al. A case series of androgen use in breast cancer survivors with sexual dysfunction. J Sex Med, 2007, 4, p. 1769–1774.

22. Leiblum, SR., Koochaki, PE., Rodenberg, CA., et al. Hypoactive sexual desire disorder in postmenopausal women: US results from the Women’s International Study of Health and Sexuality (WISHeS). Menopause, 2006, 3, p. 46-56.

23. Masters, W., Johnson, V. Human sexual response. Boston: Little Brown, 1966.

24. Nappi, R., Dean, J., Herbert, A., et al. Decreased Sexual Desire Screener (DSDS) for diagnosis of Hypoactive Sexual Desire Disorder (HSDD) in European women. J Sex Med, 2009, 6, 2 (suppl), p. 46.

25. Nijland, EA., Schultz, WCMW., Nathorst-Boös, J., et al. Tibolone and transdermal E2/NETA for the treatment of female sexual dysfunction in naturally menopausal women: Results of a randomized active-controlled trial. J Sex Med, 2008, 5, p. 646–656.

26. Pastor, Z. Klasifikace a etiologie ženských sexuálních dysfunkcí, Sexologia, 2007, 2, s. 15-23.

27. Pastor, Z. Sexualita ženy. Praha: Grada Publishing, 2007.

28. Pfaff, DW. Drive: Neurobiological and molecular mechanisms of sexual motivation. Cambridge: MIT Press, 1999.

29. Pfaus, JG. Pathways of sexual desire. J Sex Med, 2009, 6, p. 1506-1533.

30. Rosen, RC., et al. Correlates of sexually-related personal distress in women with low sexual desire. J Sex Med, 2009, 6, p. 1549-1560.

31. Segraves, R., Woodard, T. Female Hypoactive Sexual Desire Disorder: history and current status. J Sex Med, 2006, 3, p. 408–418.

32. Sexual Interest and Desire Inventory – Female [online]. Last revision 30.8. 2004. [cit 2009-08-03]. Dostupný na WWW: <http://www.isswsh.org/pdf/SIDIF%20final%20May%202004.pdf>..

33. Shifren, JL., Monz, BU., Russo, PA., et al. Sexual problems and distress in United States women: Prevalence and correlates. Obstet Gynecol, 2008, 112, p. 970-978.

34. Snabes, M., Simes, S. Approved hormonal treatments for HSDD: an unmet medical need. J Sex Med, 2009, 6, p. 1846-1849.

35. Trudel, G., Marchand, A., Ravart., M., et al. The effect of cognitive behavioral group treatment program on hypoactive sexual desire in women. Sex Rel Ther, 2001, 16, p. 145-164.

36. World Health Organisation. ICD-10: International statistical classification of diseases and related health problem. Geneva, 1992.