L-arginin in prevention and treatment of pre-eclampsia

Česká verzia

Authors: L. Vacula
Authors place of work: Gynekologicko-porodnické oddělení, Kroměřížská nemocnice, a. s., Kroměříž, primář MUDr. J. Přibík
Published in the journal: Ceska Gynekol 2013; 78(2): 181-186

Summary

Objective:
It is to show the possible relationship between the patofysiology of pre-eclampsia in the body of a human with a relative lack of L-arginine and its potential connection with a nitrogen metabolism. This study also suggests the further utilization of above mentioned knowledges in a prevention and a treatment of pre-eclampsia.

Design:
Literary overview.

Setting:
Gynaecology and Obstetric Department of the Hospital Kromeriz, Inc., Kromeriz.

Methods:
The background research of studies and issues published already in medical professional journals, bulletins and medical web databases.

Conclusion:
To provide L-arginine to pregnant women as a dietary supplement concerns no risk and is an easy precaution. L-arginine can reduce the occurrance of pre-eclampsia in women with a potential high risk of its developement. The most important transmitter substance that makes L-arginine work is the dioxide nitrogen. So far, it has been the outmost possibility how to influence the patofysiology of Pre-eclampsia The lack of L-arginine and its influence on the nitrogen metabolism is likely, but there is also a great need for further research.

Keywords:
pre-eclampsia – L-arginine – dioxide nitrogen – NO synthase – dysfunction of endothelium – urea cycle

Zdroje

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