Nine-valent HPV vaccine - new generation of HPV vaccine

Česká verzia

Authors: Tomáš Fait ^1,2 ; V. Dvořák ^1,4; R. Pilka ^1,3
Authors place of work: HPV College o. s., prezident MUDr. J. Ondruš, CSc., MIAC ¹; Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc. ²; Porodnicko-gynekologická klinika FN a LP UP, Olomouc, přednosta prof. MUDr. R. Pilka, Ph. D. ³; Centrum ambulantní gynekologie a primární péče, Brno ⁴
Published in the journal: Ceska Gynekol 2015; 80(6): 397-400

Summary

Objective:
To evaluate current knowledge about new generation of HPV vaccine – nine-valent vaccine Gardasil9.

Design:
Review article.

Results:
The nine-valent vaccine against HPV 6/11/16/18/31/33/45/52/58 could improve efficacy of quadrivalent vaccine from 70 to 90 percent for cervical cancer. In addition this vaccine has covered around85-90% of HPV-related vulvar, vaginal and anal cancers. Efficacy and immunogenicity against HPV 6/11/16/18 is the same as for quadrivalent vaccine. Efficacy against HPV 31/33/45/52/58 associated lesions is 97%.

Keywords:
HPV infection, prevention, nine-valent HPV vaccine

Zdroje

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