The importance of maternal microbiome in pregnancy

Česká verzia

Authors: J. Záhumenský; J. Hederlingová; Petra Pšenková
Authors place of work: II. gynekologicko-pôrodnícka klinika LF UK a UNB, Nemocnica Ružinov prednosta doc. MUDr. J. Záhumenský, Ph. D.
Published in the journal: Ceska Gynekol 2017; 82(3): 211-217

Summary

Objective:
To bring the most actual published findings of the influence of maternal microbiome on the development of pregnancy and possibilities of its adjusting.

Design:
Review.

Setting:
2^nd Department of Gyneacology and Obstetrics of the Faculty of Medicine and the University Hospital, Bratislava.

Methods:
Review of the literature.

Conclusions:
The appearance of microbes on various body surface areas determines the overall health status of the individual in significant manner. The change in composition of microbioma in pregnant woman is well known. It was believed that the placenta and the body of the newborn is sterile environment. Modern diagnostic methods proved the presence of microorganisms inside the fetoplacentar unit without the signs of inflammation. Mutual interaction between the immune system of the mother, microbioma and immune system of the newborn can decrease the risk of serious obstetrical syndromes as well as define the lifelong health status of the newborn. The risk can be decreased by the administration of probiotics during the pregnancy.

Keywords:
microbioma, microbiota, preeclampsia, gestational diabetes mellitus, atopy

Zdroje

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