Essential Hypertension and White Coat Hypertension in Children and Adolescents
Primární hypertenze a hypertenzní fenomén bílého pláště u dětía adolescentů
24hodinové monitorování krevního tlaku (ABPM) umožňuje přesnější zhodnocení krevního tlaku (TK) v pod-mínkách běžného prostředí pacienta. Ve studiích na dospělé populaci korelují výsledky ABPM mnohem lépes postižením cílových orgánů než hodnoty příležitostného TK a poskytují také citlivější údaje o všeobecné prognózeve smyslu morbidity a mortality. Cílem této studie bylo vyhodnocení ABPM v podmínkách blízkých populačnístudii. Do studie bylo zařazeno 115 dětí a adolescentů ve věku 8 - 20 let (82 chlapců a 33 dívek) odeslaných 25pediatry za období dvou let na základě opakovaně naměřených zvýšených hodnot příležitostného TK. Na základěvýsledku ABPM bylo 51 jedinců (44 %) označeno jako fenomén bílého pláště (FBP). Ze 64 hypertenzních pacientů7 (11 %) mělo prokázanou sekundární hypertenzi, zbytek - 57 (89 %) mělo předpokládanou primární hypertenzi.Pacienti s hypertenzí měli noční pokles krevního tlaku významně nižší než jedinci s FBP (systolický se lišilv průměru o 2,7 %; p = 0,003; diastolický o 2,5 %; p = 0,04). Pacienti s hypertenzí měli významně vyšší hodnoty24hodinového tepového tlaku (59,6 ± 7,3 torrů) ve srovnání s jedinci s FBP (53,3 ± 5,3 torrů), p < 10 -5 . Parametrylevé komory byly větší u hypertenzních pacientů ve srovnání s jedinci s FBP (tloušťka zadní stěny levé komory 8,4± 1,0 mm u hypertenzních vs. 8,0 ± 1,1 mm u FBP (p = 0,047) a index hmotnosti levé komory 81,8 ± 13,8 g/m 2 vs.74,3 ± 12 g/m 2 resp.; p = 0,003).
Klíčová slova:
ambulantní monitorování krevního tlaku (ABPM), fenomén bílého pláště, děti, hypertenze,
Authors:
Š. Rucki
Authors‘ workplace:
Dětské oddělení Nemocnice, Třinec
Published in:
Čes-slov Pediat 2000; (4): 208-214.
Category:
Overview
24-hour ambulatory blood pressure monitoring (ABPM) provides more accurate assessment of blood pressure(BP) in the patient’s common environment. The results of ABPM in the adult population have a much bettercorrelation with end organ damage than casual blood pressure and seem to provide more sensitive data of thegeneral prognosis in terms of morbidity and mortality. The objective of this study was to evaluate the ABPM ina setting close to a population study. 115 children and adolescents aged 8 - 20 years (82 boys and 33 girls) withrepeatedly elevated conventional BP readings in 25 primary care physicians’ and pediatricians’ offices wereincluded to participate in this study in the course of two years. Based on the results of the ABPM 51 subjects (44%)were labelled as white coat hypertension (WCH). Of 64 hypertensive subjects 7 (11%) were known to havea secondary cause of hypertension, the rest - 57 (89%) were assumed to suffer from essential hypertension. Thenocturnal dipping of blood pressure was significantly lower in hypertensive subjects when compared with WCH(the difference of systolic dipping was 2.7% on average, p = 0.003; the difference of diastolic dipping was 2.5%;p = 0.04). 24-hours pulse pressure values were significantly higher in hypertensive subjects (59.6 ± 7.3 mm Hg)compared with WCH (53.3 ± 5.3 mm Hg); p < 10 -5 . The left ventricular measurements in hypertensive subjects werehigher when compared with WCH (left ventricle posterior wall thickness 8.4 ± 1 mm in hypertensive vs. 8.0 ± 1.1 mmin WHC (p = 0.047) and left ventricular mass index 81.8 ± 13.8 g/m 2 vs. 74.3 ± 12 g/m 2 respectively; p = 0.003).
Key words:
ambulatory blood pressure monitoring (ABPM), white coat hypertension, children, hypertension,
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2000 Issue 4
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