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Observation of risk factors on atherosclerosis in obese children


Authors: L. Zlatohlávek 1;  Z. Urbanová 2;  M. Vráblík 1;  M. Prusíková 1;  R. Češka 1
Authors place of work: III. interní klinika VFN a 1. LF UK, Praha přednosta prof. MUDr. Š. Svačina, DrSc. 1;  Klinika dětského a dorostového lékařství VFN a 1. LF UK, Praha přednosta prof. MUDr. J. Zeman, DrSc. 2
Published in the journal: Čes-slov Pediat 2011; 66 (3): 153-156.
Category: Original Papers

Summary

Primary prevention of atherosclerosis should begin in childhood. To the integral part of the complex care of children at risk belongs a spa treatment. Results of the one-month spa treatment of 164 children with obesity, dyslipidemia and hypertension are demonstrated. Total cholesterol level decreased from 4.54 to 3.66 mmol/L, LDL cholesterol from 2.79 to 2.09 mmol/l, triglycerides from 1.01 to 0.82 mmol/L, Lp(a) from 0.28 to 0.20 mmol/l, apo B from 0.88 to 0.75 mmol/l, insulin from 13.54 to 11.5 mIU/l, GGT from 0.33 to 0.22 mmol/l. The reduction of all parameters was statistically significant (p<0.001) as well as the reduction of BMI and anthropometric measurements. Only blood glucose value remained unchanged following 30 days of spa treatment. The decrease of total cholesterol was followed also by a decrease of HDL cholesterol from 1.31 to 1.11 mmol/l, and apo A from 1.29 to 1.08 mmol/l.

In conclusion, results of the spa treatment for children with the serious risk factors of atherosclerosis is effective and it should be an integral part of the care for these children.

Key words:
obesity, dyslipidemia, children, atherosclerosis


Zdroje

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Štítky
Neonatology Paediatrics General practitioner for children and adolescents
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