Benign infantile seizures associated with noroviral gastroenteritis

Česká verzia

Authors: J. Melek ¹; J. Malý ¹; Š. Štefáčková ²; V. Štěpánová ³; P. Kosina ⁴; O. Pozler ¹
Authors place of work: Dětská klinika LF a FN, Hradec Králové, přednosta prof. MUDr. M. Bayer, CSc. ¹; Neurologická klinika Fakultní nemocnice, Hradec Králové, přednosta MUDr. R. Taláb, CSc. ²; Ústav klinické mikrobiologie Fakultní nemocnice, Hradec Králové, přednosta doc. RNDr. V. Buchta, CSc. ³; Klinika infekčních nemocí Fakultní nemocnice, Hradec Králové, přednosta doc. MUDr. S. Plíšek, Ph. D. ⁴
Published in the journal: Čes-slov Pediat 2012; 67 (3): 187-191.
Category: Case Report

Summary

Case reports of two children with the case history of diarrhea disease followed by suddenly developed neurological symptomatology at the age of 15 and 17 months are described. The clinical, manifestations and examinations performed made it possible to establish the diagnosis of benign seizures associated with noroviral gastroenteritis.

Benign infantile seizures associated with noroviral gastroenteritis represent a relatively new unit described mainly in Asia. Noroviruses belong to the most frequent provoking agents. The disease affects so far healthy individuals at the age of 15–21 months. The main clinical manifestations include several although not many says lasting afebrile gastroenteritis, followed by seizure attacks, most often generalized tonic clonic seizures. The seizures tend to be rather recurrent in the first 24 hours and are rather resistant to anticonvulsant therapy. Noroviruses are often demonstrated in the stools. The basic biochemical parameters of serum, examination of liquor and imaging examination of the brain are often normal. Interictal EEG record may be normal or detecting abnormities which adjust in time. The prognosis despite apparently serious condition is usually excellent. The children further develop in a normal way and do not need anticonvulsant therapy.

Key words:
noroviruses, seizures, gastroenteritis, rotaviruses

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