Current options for assessment of platelet function in neonates
Authors:
Z. Straňák 1,2
Authors place of work:
Ústav pro péči o matku a dítě, Praha
1; 3. lékařská fakulta UK, Praha
2
Published in the journal:
Čes-slov Pediat 2017; 72 (8): 454-456.
Souborný referát věnovaný profesoru Ottovi Hrodkovi, zakladateli výzkumu poruch hemostázy u novorozenců
Summary
Hemostasis is a dynamic process that begins in the fetus within intrauterine development. Blood platelets plays an important part of hemostasis.
Functional and morphological changes of neonatal platelets are presented in this review article as well the historical contribution of Professor Otto Hrodka in the diagnosis of neonatal hemostasis disorders Futhermore current possibilities in the diagnosis of platelet dysfunction in the neonatal period are expressed (evaluation of neonatal platelet aggregation, flow cytometry, agregometry, thrombelastography and rotational thrombelastometry).
Key words:
neonatal platelets, hemostasis disorders, current diagnostic methods
Zdroje
1. Hrodek O. Contribution to the pathogenesis of hemorrhagic diathesis in newborn infants. Čs Pediat 1955 Jul; 10 (6): 424–431
2. Hrodek O. On the development of coagulation factors in early neonatal life. Ann Paediatr 1959 Mar; 192 (3): 129–142.
3. Hrodek O. Development of blood platelet function in the early newborn period. Čs Pediat 1964 Feb; 19: 107–111.
4. Hrodek O, Heřmanský F. Thrombelastographic study in the newborn. Ann Paediatr 1960 Apr; 194: 246–254.
5. Hrodek O, Mydlil V, Housková J, Velisková V. Fibrinolysis, fibrinogen and trhombin time in newborns. Biol Neonate 1976; 28 (1–2): 106–112.
6. Del Vecchio A, Motta M, Romagnoli C. Neonatal platelet function. Clin Perinatol 2015 Sep; 42 (3): 625–638.
7. Ozaki Y, Tamura S, Suzuki-Inoue K. New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2. Thromb J 2016 Oct 4; 14 (Suppl 1): 27.
8. Toulon P. Developmental hemostasis: laboratory and clinical implications. Int J Lab Hematol 2016 May; 38 (Suppl 1): 66–77.
9. Hvas AM, Favaloro EJ. Platelet function testing in pediatric patients. Expert Rev Hematol 2017 Apr; 10 (4): 281–288.
10. Hanmod SS, Jesudas R, Kulkarni R, Chitlur M. Neonatal hemostatic disorders: Issues and challenges. Semin Thromb Hemost 2016 Oct; 42 (7): 741–751.
11. Radicioni M, Mezzetti D, Del Vecchio A, Motta M. Thromboelastography: might work in neonatology too? J Matern Fetal Neonatal Med 2012 Oct; 25 (Suppl 4): 18–21.
Štítky
Neonatology Paediatrics General practitioner for children and adolescentsČlánok vyšiel v časopise
Czech-Slovak Pediatrics
2017 Číslo 8
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